Prescription Required.
Simvastatin (the active ingredient): A member of the statin class of drugs.Inactive ingredients: These vary depending on the specific brand and formulation. Always check the product label for a complete list.
Lowering high cholesterol (hypercholesterolemia) and triglycerides.
Reducing the risk of cardiovascular events (heart attack, stroke) in patients with high cholesterol or other risk factors.
Slowing the progression of atherosclerosis (hardening of the arteries).
Zosta 5mg Tab (Simvastatin) inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis in the liver. By reducing cholesterol production, simvastatin lowers LDL ('bad') cholesterol levels and increases HDL ('good') cholesterol levels.
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Dosage varies greatly depending on individual needs and response. Always follow your doctor's instructions.
Typically taken orally once daily, often in the evening.
Do not crush, chew, or break the tablets unless specifically instructed by your doctor.
Muscle aches and pains (myalgia) – ranging from mild to severe (rarely rhabdomyolysis).
Headache
Gastrointestinal issues (e.g., constipation, diarrhea, nausea)
Liver enzyme elevation (rarely liver damage)
Allergic reactions (rash, itching, swelling)
Moderate alcohol consumption is generally acceptable, but excessive alcohol use may increase the risk of liver damage. Discuss with your doctor.
Simvastatin generally does not impair driving or operating machinery, but potential side effects such as dizziness or fatigue should be considered.
Simvastatin is contraindicated in pregnancy and breastfeeding women. Alternative treatment options are necessary.
Not typically used in children. Dosage and safety in children have not been fully established.
Generally well-tolerated in patients with mild to moderate kidney disease. Dosage adjustments may be needed in those with severe kidney impairment.
Caution is advised in patients with liver disease. Liver function tests should be monitored.
Your doctor or pharmacist
The prescribing information for your specific simvastatin product
Reputable medical websites (e.g., Mayo Clinic, NHS, MedlinePlus)
