Is the active ingredient.
Adjunctive therapy for partial seizures (with or without secondary generalization) in adults.
Adjunctive therapy for myoclonic seizures in adults with juvenile myoclonic epilepsy.
The exact mechanism isn't fully understood, but Zonimid 50mg Cap (Zonisamide) is thought to block sodium channels and enhance the action of GABA, thereby reducing neuronal excitability and preventing seizure activity. It may also affect other neurotransmitter systems.
Store at room temperature (20-25°C), away from moisture and light. Keep out of reach of children.
Dosage is individualized and should be determined by a physician.
Typically started at a low dose and gradually increased as tolerated.
Usually taken twice daily with or without food.
Never abruptly stop taking zonisamide; it should be gradually tapered under medical supervision.
Drowsiness
Dizziness
Fatigue
Headache
Nausea
Vomiting
Kidney stones (risk increased with dehydration)
Weight loss
Skin rash
Depression
Anxiety
Suicidal thoughts (rare but serious)
Alcohol should be avoided or consumed in moderation as it may increase the risk of drowsiness and other side effects.
Avoid driving or operating machinery until you know how zonisamide affects you. Drowsiness and dizziness are common side effects.
Inform your doctor immediately if you are pregnant, planning to become pregnant, or breastfeeding. Zonisamide may pose risks to the fetus or infant.
Use in children is generally not recommended due to limited data on efficacy and safety.
Zonisamide can increase the risk of kidney stones, especially in individuals with a history of kidney problems. Regular monitoring of kidney function may be necessary.
Liver function should be monitored, particularly in patients with pre-existing liver disease, as zonisamide can affect liver enzymes.
Consult your physician or pharmacist for complete information and the most up-to-date prescribing information.
