Epalrestat

A medication that helps to prevent damage to nerves in people with diabetes.

Methylcobalamin

A form of vitamin b12 that is essential for the proper functioning of nerves and red blood cells.

Diabetic neuropathy (nerve damage caused by diabetes)

May be used to manage symptoms such as pain, tingling, numbness, and weakness in the feet and hands.

Epalrestat works by inhibiting the enzyme aldose reductase, which is involved in the production of sorbitol, a sugar alcohol that can accumulate in nerve cells and contribute to nerve damage. Methylcobalamin, as a form of vitamin B12, supports the normal function of the nervous system.

Store the medication at room temperature, away from heat, moisture, and direct sunlight. Keep it out of reach of children and pets.

The dosage and frequency of administration of Epalrestat + Methylcobalamin will be determined by your doctor based on your individual needs and medical history.

It is typically taken orally, with or without food.

Follow your doctor's instructions carefully and do not change your dosage without consulting with them.

Common side effects may include: headache, nausea, vomiting, diarrhea, constipation, dizziness, and weakness.

Alcohol Consumption

Alcohol can interact with some medications and should be consumed in moderation or avoided while taking Epalrestat + Methylcobalamin. Consult your doctor for specific advice.



While Driving or Operating Machinery

Epalrestat + Methylcobalamin may cause dizziness or weakness, which can impair your ability to drive or operate machinery. Do not drive or operate machinery if you experience these side effects.



Pregnant & Breastfeeding Women

It is not recommended to take Epalrestat + Methylcobalamin during pregnancy or breastfeeding unless specifically directed by your doctor. Consult with your healthcare provider about the potential risks and benefits.



Children

The safety and effectiveness of Epalrestat + Methylcobalamin in children have not been established. It is generally not recommended for use in children.



Kidney

If you have kidney problems, your doctor may need to adjust your dosage or monitor you closely while taking Epalrestat + Methylcobalamin.



Liver

If you have liver problems, your doctor may need to adjust your dosage or monitor you closely while taking Epalrestat + Methylcobalamin.

The official prescribing information for Epalrestat + Methylcobalamin

National Institutes of Health (NIH) website

American Diabetes Association (ADA) website

Other reputable medical sources