Gliclazide

A sulfonylurea drug that stimulates the pancreas to release more insulin.

Metformin

A biguanide drug that improves insulin sensitivity and reduces glucose production by the liver.

Type 2 diabetes mellitus, particularly when diet and exercise alone are insufficient to control blood sugar levels.

Used in patients where a combination of gliclazide and metformin is deemed appropriate by their doctor.

Zeformin Xr 60mg Tab (Gliclazide + Metformin) work synergistically to lower blood glucose levels. Gliclazide increases insulin secretion from the pancreas, while metformin enhances insulin sensitivity in peripheral tissues and reduces hepatic glucose production. This combined action leads to improved glycemic control.

Store in a cool, dry place, protected from light and moisture. Keep out of reach of children. Discard according to instructions provided by your pharmacist or doctor.

Dosage should be determined and adjusted by a healthcare professional based on individual needs and response.

Generally, the medication is taken orally, usually with meals, to minimize gastrointestinal side effects.

Do not adjust the dose without consulting your doctor.

Lactic acidosis (rare but serious): Characterized by muscle pain, weakness, shortness of breath, and unusual tiredness. Seek immediate medical attention if suspected.

Hypoglycemia (low blood sugar): Symptoms include sweating, trembling, dizziness, confusion, and rapid heartbeat.

Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal pain.

Vitamin B12 deficiency (longterm use)

Allergic reactions: Rash, itching, swelling.

Alcohol Consumption

Alcohol consumption should be limited or avoided as it can increase the risk of hypoglycemia and lactic acidosis.



While Driving or operating Machinery

May cause dizziness or hypoglycemia, affecting ability to drive or operate machinery. Avoid if symptoms occur.



Pregnant & Breastfeeding Women

Generally not recommended during pregnancy or breastfeeding. Consult your doctor for alternative treatment options.



Children

Not typically indicated for children. Dosage and use should be determined by a physician.



Kidney

Requires careful monitoring and dose adjustment in patients with kidney disease. May be contraindicated in severe cases.



Liver

Requires careful monitoring and dose adjustment in patients with liver disease. May be contraindicated in severe cases.

Please consult your doctor or pharmacist for detailed information and references to specific studies.

Refer to the official drug monograph for complete details.