Roxithromycin

Is a macrolide antibiotic, specifically a semi-synthetic derivative of erythromycin. it is typically available as a tablet or capsule formulation.

Roxithromycin is primarily used to treat bacterial infections, including:

Respiratory tract infections (e.g., bronchitis, pneumonia)

Skin and soft tissue infections (e.g., impetigo, cellulitis)

Genital infections (e.g., chlamydia, gonorrhea)

Other infections, such as Lyme disease and Legionnaires' disease.

Zedan P 50mg Tablet (Roxithromycin) works by inhibiting bacterial protein synthesis, which is essential for their growth and survival. It binds to the 50S ribosomal subunit of bacteria, preventing the formation of peptide bonds and disrupting protein production.

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Store roxithromycin tablets or capsules in a cool, dry place, away from direct sunlight and moisture.

1

Keep it out of reach of children and pets.

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Do not use roxithromycin after the expiry date printed on the packaging.

The dosage and duration of roxithromycin treatment vary depending on the type and severity of infection, as well as the individual's age, weight, and kidney function.

It is crucial to follow your doctor's instructions carefully.

Roxithromycin is typically taken orally with or without food.

Avoid taking it with grapefruit juice, as it can interfere with its metabolism.

Do not crush, chew, or break the tablets or capsules.

Roxithromycin can cause various side effects, some of which are common and others less frequent. The most common side effects include:

Nausea

Vomiting

Diarrhea

Stomach pain

Headache

Dizziness

Skin rash

Itching

Liver function abnormalities

Abnormal heart rhythm (rare but serious)

Alcohol Consumption

Alcohol consumption may enhance the risk of certain side effects, including dizziness and nausea. It is generally advisable to avoid alcohol while taking roxithromycin.



While Driving or Operating Machinery

Roxithromycin can cause dizziness and drowsiness, which may impair your ability to drive or operate machinery safely. If you experience these side effects, avoid these activities.



Pregnant & Breastfeeding Women

Roxithromycin should not be used during pregnancy unless the potential benefits outweigh the risks to the fetus. It is not recommended for breastfeeding women, as it may pass into breast milk.



Children

The use of roxithromycin in children should be carefully considered and only prescribed by a doctor.



Kidney

In patients with impaired kidney function, the dosage of roxithromycin may need to be adjusted. Your doctor will monitor your kidney function during treatment.



Liver

Roxithromycin can affect liver function, especially in patients with pre-existing liver problems. Your doctor may monitor your liver function during treatment.

1. Micromedex® (https://www.micromedexsolutions.com/)

2. Epocrates® (https://www.epocrates.com/)

3. National Institutes of Health (https://www.nih.gov/)