Clozapine

Is the active ingredient.

Treatmentresistant schizophrenia

Schizophrenia with a high risk of suicide

Zaporil 100mg Tab (Clozapine) is an atypical antipsychotic. Its exact mechanism isn't fully understood, but it's believed to work by blocking dopamine and serotonin receptors in the brain, thereby reducing psychotic symptoms.

Store at room temperature, away from light and moisture. Keep out of reach of children. Dispose of unused medication properly.

Dosage is determined by a doctor and is typically started at a low dose and gradually increased.

It's usually administered orally, as a tablet or liquid.

Regular blood monitoring is crucial to check for agranulocytosis.

Seizures

Myocarditis (inflammation of the heart muscle)

Hypotension (low blood pressure)

Constipation

Sedation

Weight gain

Increased risk of metabolic syndrome

Drooling

Drowsiness

Alcohol Consumption

Alcohol should be avoided or severely limited as it can potentiate the sedative effects of clozapine and increase the risk of side effects.



While Driving or operating Machinery

Avoid driving or operating machinery until you know how clozapine affects you, due to potential drowsiness and impaired coordination.



Pregnant & Breastfeeding Women

Use during pregnancy and breastfeeding should be carefully considered by the doctor due to potential risks to the fetus or infant. The benefits must outweigh the potential risks.



Children

Not typically prescribed for children unless specifically indicated by a specialist.



Kidney

Dosage adjustment may be necessary in patients with impaired kidney function.



Liver

Dosage adjustment may be necessary in patients with impaired liver function.

Your physician's instructions and medication information leaflet

The prescribing information provided by the manufacturer

Reputable medical websites such as the FDA and NHS (depending on your location)