Zambri 5mg Tablet: Price, Use, Benefit, Side Effect

Zambri 5mg Tablet

Marketer

Zydus Cadila

Composition

Ambrisentan (5mg)

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About Zambri 5mg Tablet

Zambri 5mg Tablet (Ambrisentan) is a medication used to treat pulmonary arterial hypertension (PAH). It works by relaxing blood vessels in the lungs, improving blood flow. Common side effects include headache, swelling, and nasal congestion. It's crucial to inform your doctor about all other medications you are taking, including alcohol consumption, and any pre-existing medical conditions, especially liver and kidney disease. Regular liver function tests are necessary during treatment. Pregnancy and breastfeeding are contraindicated. Never adjust your dosage without consulting your doctor.

Ingredients

Directions for Use

How Drug Works

Storage & Handling

Drug Dosage

Side Effects

Safety Consideration or Warnings

References

Ingredients of Zambri 5mg Tablet

Ambrisentan

Is the active ingredient.

Direction for Use of Zambri 5mg Tablet

Treatment of pulmonary arterial hypertension (PAH) in patients classified as WHO Functional Class II or III.

Specifically, it's used to improve exercise capacity and delay clinical worsening in PAH patients.

How Zambri 5mg Tablet Works

Zambri 5mg Tablet (Ambrisentan) is an endothelin receptor antagonist. It selectively blocks the binding of endothelin-1 to its ETA receptors. Endothelin-1 is a potent vasoconstrictor, and by blocking its action, ambrisentan helps to relax and widen blood vessels in the lungs, improving blood flow and reducing pulmonary vascular resistance.

Storage and Handling of Zambri 5mg Tablet

Store at controlled room temperature 20°C to 25°C (68°F to 77°F). Protect from light and moisture. Keep out of reach of children.

Dosage of Zambri 5mg Tablet

The recommended starting dose is typically 5 mg once daily.

The dose may be increased to 10 mg once daily based on individual patient response and tolerability.

It's crucial to follow your doctor's prescribed dosage and administration instructions precisely.

Side effects of Zambri 5mg Tablet

Headache

Peripheral edema (swelling in the extremities)

Nasal congestion

Dizziness

Upper respiratory tract infection

Fatigue

Syncope (fainting)

Safety Consideration or Warnings

Alcohol Consumption

The interaction between ambrisentan and alcohol is not fully characterized; consult your doctor.

While Driving or operating Machinery

Ambrisentan may cause dizziness or syncope. Avoid driving or operating machinery until you know how it affects you.

Pregnant & Breastfeeding Women

Ambrisentan is contraindicated in pregnancy. It's unknown if ambrisentan is excreted in breast milk; breastfeeding is not recommended while taking this medication.

Children

Safety and effectiveness in pediatric patients have not been established.

Kidney

Dosage adjustments may be necessary in patients with severe kidney impairment. Consult your doctor.

Liver

Ambrisentan is metabolized by the liver. Regular monitoring of liver enzymes is essential. Dosage adjustments or discontinuation may be needed for patients with liver dysfunction.

References

Please consult your physician or pharmacist for detailed information and specific prescribing information.

Refer to the official drug monograph for complete details.

Last Updated On 04 Dec. 2025 | 07:05 PM (IST)

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