Dapagliflozin

A sodium-glucose co-transporter 2 (sglt2) inhibitor.

Metformin

A biguanide medication that helps control blood sugar levels.

Type 2 diabetes mellitus (T2DM) to improve glycemic control, especially in patients who are unable to achieve adequate glycemic control with metformin alone.

Dapagliflozin works by blocking the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine. This results in lower blood sugar levels. Metformin reduces glucose production in the liver and improves insulin sensitivity, enhancing glucose uptake by the body's cells.

Store at room temperature, away from direct sunlight and moisture. Keep out of reach of children.

The dosage of dapagliflozin/metformin should be individualized based on your specific needs and medical history.

It is typically taken once daily with or without food.

Follow your doctor's instructions carefully.

Common side effects include:

Urinary tract infections

Genital yeast infections

Nausea

Vomiting

Diarrhea

Stomach pain

Lactic acidosis (rare but serious)

Low blood sugar (hypoglycemia) (rare, especially when used in combination with insulin or other medications that lower blood sugar)

Dehydration

Increased risk of bone fractures

Alcohol Consumption

Limit alcohol consumption as it may increase the risk of lactic acidosis.



While Driving or Operating Machinery

Dapagliflozin/metformin may cause dizziness or hypoglycemia, which can impair your ability to drive or operate machinery. Avoid driving or operating machinery if you experience these side effects.



Pregnant & Breastfeeding Women

This medication is not recommended during pregnancy or breastfeeding. Consult your doctor for advice.



Children

Dapagliflozin/metformin is not approved for use in children.



Kidney

Dapagliflozin/metformin should be used with caution in patients with kidney disease. Your doctor may need to adjust your dosage or monitor your kidney function regularly.



Liver

Dapagliflozin/metformin should be used with caution in patients with liver disease. Your doctor may need to adjust your dosage or monitor your liver function regularly.

Your doctor or pharmacist.

The medication leaflet provided with your prescription.

The Food and Drug Administration (FDA) website.