Prescription Required.Why?
A sulfonylurea drug that stimulates the pancreas to release more insulin.
A biguanide that improves insulin sensitivity and reduces glucose production by the liver.
A thiazolidinedione (tzd) that improves insulin sensitivity by acting on cells.
Type 2 diabetes mellitus when diet and exercise alone are insufficient to control blood sugar levels.
Used in patients who require a combination of medications to effectively manage their blood glucose levels.
This triple combination medication works synergistically to lower blood glucose levels. Glimepiride increases insulin secretion, metformin decreases hepatic glucose production and improves insulin sensitivity, while pioglitazone enhances insulin sensitivity in peripheral tissues.
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Dosage should be determined by a healthcare professional based on individual patient needs and response to treatment.
Generally, the medication is taken orally with food to minimize gastrointestinal side effects.
It's crucial to follow your doctor's prescribed dosage and schedule precisely.
Gastrointestinal issues: Nausea, vomiting, diarrhea, and abdominal pain (more common with metformin).
Hypoglycemia (low blood sugar): Symptoms include shakiness, sweating, dizziness, confusion, and rapid heartbeat.
Weight gain (particularly with pioglitazone).
Fluid retention (with pioglitazone).
Allergic reactions (rash, itching, swelling).
Alcohol consumption can increase the risk of hypoglycemia and should be limited or avoided.
Hypoglycemia can impair judgment and coordination; avoid driving or operating machinery if experiencing low blood sugar symptoms.
Use is generally not recommended during pregnancy or breastfeeding. Consult your doctor immediately if you become pregnant while taking this medication.
Not approved for use in children.
Requires careful monitoring in patients with kidney disease, as metformin can accumulate and increase the risk of lactic acidosis.
Requires careful monitoring in patients with liver disease, as pioglitazone can potentially worsen liver function.
Consult your doctor or pharmacist for detailed information and references.
