Prescription Required.Why?
A monobactam antibiotic.
Treatment of infections caused by susceptible strains of gramnegative bacteria.
Treatment of lower respiratory tract infections (pneumonia).
Treatment of urinary tract infections (UTIs).
Treatment of intraabdominal infections.
Treatment of skin and skin structure infections.
Treatment of bacterial septicemia (bloodstream infections).
Trezam 250mg Inj (Aztreonam) inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), specifically PBP3, in gram-negative bacteria. This prevents the formation of peptidoglycan, a crucial component of the bacterial cell wall, leading to bacterial cell death.
Store at controlled room temperature (20°C to 25°C/68°F to 77°F). Protect from light and moisture. Discard any unused portion after the expiration date.
Dosage is determined by the physician based on the severity of the infection, patient's weight, and renal function.
Administered intravenously (IV) or intramuscularly (IM).
Specific dosage instructions should be followed carefully as prescribed by a doctor.
Pain at the injection site (for IM administration)
Thrombophlebitis (inflammation of a vein) (for IV administration)
Nausea
Vomiting
Diarrhea
Rash
Pruritus (itching)
Elevated liver enzymes
Avoid excessive alcohol consumption while taking Aztreonam, as it may exacerbate side effects.
Aztreonam may cause dizziness or drowsiness. Avoid driving or operating machinery if affected.
Consult your doctor before using Aztreonam if pregnant or breastfeeding. Use should be considered only when the benefits outweigh the potential risks.
Dosage adjustments may be necessary for children. A doctor should determine the appropriate dosage.
Aztreonam is primarily excreted by the kidneys. Dosage adjustment is necessary for patients with impaired renal function.
Monitor liver function during treatment, as elevated liver enzymes have been reported.
Consult your physician or pharmacist for complete prescribing information and package inserts.
Refer to reputable medical databases like MedlinePlus or the FDA website for further details.
