Primaquine

Phosphate is the active ingredient in primaquine formulations. the exact inactive ingredients can vary depending on the specific brand and formulation (tablet, liquid etc.) always check the product label for a complete list.

Primaquine is primarily used to prevent relapses of malaria caused by Plasmodium vivax and Plasmodium ovale. It is also used in combination with other antimalarial drugs to treat malaria.

It may be used to treat certain types of Pneumocystis pneumonia in combination with other medications.

Tpquin P 15mg Tablet (Primaquine) works by targeting and killing the gametocytes (sexual forms) of the malaria parasite. This prevents transmission of the parasite from one person to another through mosquito bites. It also has some activity against the liver stages of the parasite, helping to prevent relapse.

Store primaquine at room temperature, away from moisture and direct sunlight. Keep out of the reach of children. Discard any unused medication after the expiration date.

Dosage of primaquine varies greatly depending on the indication (prevention vs. treatment), patient age, weight, and liver function. It's crucial to follow your doctor's prescription precisely.

Primaquine is typically administered orally (by mouth) but dosage forms can differ depending on the brand and formulation. It's never recommended to alter the dosage without doctor's advice.

Hemolytic anemia (a serious blood disorder, more likely in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency)

Gastrointestinal issues (nausea, vomiting, abdominal pain)

Headache

Shortness of breath

Skin rash

Alcohol Consumption

Alcohol consumption may increase the risk of side effects. Consult your doctor.



While Driving or operating Machinery

Primaquine may cause dizziness or drowsiness. Avoid driving or operating machinery if affected.



Pregnant & Breastfeeding Women

Primaquine should generally be avoided during pregnancy unless the potential benefits outweigh the risks. It's unclear whether primaquine is secreted in breast milk; consult your doctor.



Children

Dosage and safety in children should be determined by a physician considering weight and potential increased risk of side effects.



Kidney

Dose adjustments may be necessary for patients with kidney impairment. Consult your doctor.



Liver

Primaquine is metabolized by the liver. Individuals with liver disease should use primaquine with extreme caution; significant dose reductions or avoidance may be necessary. Always consult your physician.

Please consult your physician or pharmacist for specific references and detailed information. Information provided is for general knowledge only and does not constitute medical advice.