Insulin glargine is a long-acting man-made form of human insulin.

Treatment of adults and children with type 1 diabetes mellitus

Treatment of adults with type 2 diabetes mellitus when other medications, such as metformin, are not enough to control blood sugar

Insulin glargine lowers blood glucose levels by binding to insulin receptors on cells, facilitating glucose uptake and utilization, and inhibiting glucose production by the liver. Its long-acting nature provides a relatively consistent blood glucose-lowering effect over 24 hours.

Store in a refrigerator (2°C to 8°C). Do not freeze. Once removed from refrigeration, it can be stored at room temperature (up to 25°C) for up to 28 days. Protect from light. Discard after 28 days at room temperature, even if some medication remains. Always keep insulin out of reach of children and pets. Do not shake the pen or vial.

The dose of insulin glargine is individualized and determined by your doctor based on your blood glucose levels and other factors.

It is typically administered once daily at the same time each day, usually in the evening.

Insulin glargine is injected subcutaneously (under the skin) using a pre-filled pen or syringe.

Do not inject insulin glargine intravenously (into a vein) or intramuscularly (into a muscle).

Hypoglycemia (low blood sugar)

Injection site reactions (redness, swelling, itching)

Weight gain

Edema (fluid retention)

Allergic reactions (rare)

Alcohol Consumption

Alcohol can affect blood sugar levels and should be consumed in moderation or as advised by your doctor.



While Driving or operating Machinery

Hypoglycemia can impair alertness and reaction time. Do not drive or operate machinery if you feel symptoms of hypoglycemia.



Pregnant & Breastfeeding Women

Use only as directed by your doctor. Insulin glargine is generally considered safe during pregnancy and breastfeeding, but monitoring is needed.



Children

Dosage is adjusted based on the child's weight and needs. Close monitoring is required.



Kidney

Renal impairment may affect insulin glargine clearance. Dosage adjustment may be necessary.



Liver

Hepatic impairment may affect insulin glargine metabolism. Dosage adjustment may be necessary.

Please consult your physician or pharmacist for specific references and prescribing information.