Prescription Required.Why?
Is the active ingredient.
Epilepsy (both as monotherapy and adjunctive therapy)
Prevention of migraine headaches
Treatment of LennoxGastaut syndrome
Treatment of certain types of seizures
Weight management (offlabel use, requires careful medical supervision)
Topaz 200mg Tab (Topiramate)'s exact mechanism isn't fully understood, but it's believed to work through multiple pathways, including blocking sodium channels, enhancing the action of GABA (an inhibitory neurotransmitter), and antagonizing AMPA/kainate receptors. These actions help reduce the excessive neuronal activity that causes seizures and migraines.
Store at room temperature, away from moisture and heat. Keep out of reach of children.
Dosage is determined by your doctor and depends on the condition being treated and your individual response.
It's usually started at a low dose and gradually increased.
Topiramate comes in various forms: tablets, capsules, and extended-release capsules.
Follow your doctor's instructions carefully, including how to take the medication with food or water.
Numbness or tingling in the extremities (paresthesia)
Dizziness
Fatigue
Cognitive changes (difficulty concentrating, memory problems)
Weight loss
Kidney stones
Mood changes (depression, anxiety)
Vision problems
Nausea
Vomiting
Constipation
Alcohol should be avoided or significantly limited, as it can worsen side effects.
Avoid driving or operating machinery until you know how topiramate affects you, as it can cause dizziness and drowsiness.
Topiramate is not recommended during pregnancy unless the benefits clearly outweigh the risks. It can cause birth defects. It can also pass into breast milk and may affect the infant. Discuss options with your doctor.
Dosage is adjusted for children based on weight and age. Careful monitoring is needed.
Topiramate is eliminated by the kidneys. Patients with kidney problems may require dosage adjustments. Regular monitoring of kidney function is crucial.
Topiramate is primarily metabolized in the liver. Patients with liver disease may require dosage adjustments or monitoring.
Your doctor or pharmacist
The FDA's drug information website (e.g., DailyMed)
Reputable medical journals and textbooks
