Tofacitinib

Tofacitinib (active ingredient)Various inactive ingredients depending on the specific formulation (check product labeling for details)

Treatment of moderate to severe rheumatoid arthritis (RA) in adults who have had an inadequate response to methotrexate.

Treatment of moderate to severe active ulcerative colitis (UC) in adults.

Treatment of moderate to severe active psoriatic arthritis (PsA) in adults.

Treatment of moderate to severe atopic dermatitis (AD) in adults and adolescents (age 12 years and older) whose disease is not adequately controlled with topical therapies or phototherapy.

Tnib 5mg Tab (Tofacitinib) is a Janus kinase (JAK) inhibitor. It works by blocking the activity of certain JAK enzymes, which play a key role in the inflammatory process involved in various autoimmune and inflammatory conditions. By inhibiting JAK enzymes, tofacitinib reduces inflammation and improves symptoms.

Store at room temperature, away from moisture and direct sunlight. Discard any unused medication after the expiration date. Keep out of reach of children.

Dosage and frequency vary depending on the specific condition being treated and the individual patient's response. Always follow your doctor's instructions.

Tofacitinib is typically administered orally.

Increased risk of infections (serious infections possible)

Headache

Nausea

Diarrhea

Upper respiratory tract infections

Hyperlipidemia

Elevated liver enzymes

Thrombosis (blood clots)

Heart failure

Pneumonia

Alcohol Consumption

The effects of alcohol consumption while taking tofacitinib are not well-studied. Consult your physician.



While Driving or operating Machinery

Tofacitinib may cause dizziness or fatigue. Avoid driving or operating machinery until you know how this medication affects you.



Pregnant & Breastfeeding Women

Consult your doctor before using tofacitinib if you are pregnant, planning to become pregnant, or breastfeeding. It is generally not recommended during pregnancy or breastfeeding.



Children

Use in children is limited to specific conditions and ages (consult product information for specifics).



Kidney

Kidney function should be monitored, especially in patients with pre-existing kidney disease. Dose adjustment may be necessary.



Liver

Liver function should be monitored, especially in patients with pre-existing liver disease. Dose adjustment may be necessary.

Your physician

Product labeling

Reputable medical websites (e.g., FDA, Mayo Clinic)