Tenofovir Alafenamide

Tenofovir alafenamide (TAF) is the active ingredient in medications like Descovy, Odefsey, and Vemlidy.It is a type of antiviral drug known as a nucleotide reverse transcriptase inhibitor (NRTI).TAF is a newer and more potent formulation of tenofovir disoproxil fumarate (TDF), which is another commonly used antiviral medication.

Treatment of chronic hepatitis B virus (HBV) infection in adults.

Treatment of HIV1 infection in adults, in combination with other antiretroviral agents.

Prevention of HIV1 infection in adults at high risk of acquiring HIV-1 infection.

Tentide Af Tab (Tenofovir Alafenamide) (TAF) works by interfering with the activity of an enzyme called reverse transcriptase. This enzyme is essential for the HIV-1 virus to replicate itself within the body. By inhibiting reverse transcriptase, TAF prevents the virus from multiplying, reducing its levels in the blood and helping to control the infection.

Store at room temperature between 20°C and 25°C (68°F and 77°F).

The dosage of tenofovir alafenamide (TAF) will vary depending on the specific indication and the patient's individual needs.

Your doctor will determine the appropriate dosage for you.

It is important to take TAF exactly as prescribed by your doctor.

Common side effects of tenofovir alafenamide (TAF) include headache, nausea, diarrhea, and fatigue.

Serious side effects are rare but may include kidney problems, liver problems, and bone loss.

Alcohol Consumption

Alcohol consumption may increase the risk of side effects from tenofovir alafenamide (TAF). It is important to talk to your doctor about alcohol consumption while taking TAF.



While Driving or operating Machinery

TAF does not typically impair mental alertness or coordination. However, it is important to be aware of any potential side effects that may affect your ability to drive or operate machinery.



Pregnant & Breastfeeding Women

It is generally recommended to avoid taking tenofovir alafenamide (TAF) during pregnancy and breastfeeding.



Children

The safety and effectiveness of TAF have not been established in children.



Kidney

TAF can affect kidney function, particularly in people with pre-existing kidney problems. It is important to have regular kidney function tests while taking TAF.



Liver

TAF can affect liver function, particularly in people with pre-existing liver problems. It is important to have regular liver function tests while taking TAF.

U.S. Food and Drug Administration (FDA): https://www.fda.gov/

Centers for Disease Control and Prevention (CDC): https://www.cdc.gov/

National Institutes of Health (NIH): https://www.nih.gov/