Is the main active ingredient. specific formulations may contain additional excipients (inactive ingredients) such as fillers, binders, and preservatives. always check the product label for a complete list of ingredients.
Prevention of organ rejection in kidney, liver, and heart transplant recipients.
Treatment of severe atopic dermatitis (eczema) in adults and children who have not responded to other treatments.
Tacrolimus Ointment 0.1% W/W 10gm (Tacrolimus) is an immunosuppressant drug. It works by inhibiting calcineurin, a protein involved in the activation of T-cells, which are crucial components of the immune system. By suppressing T-cell activity, tacrolimus reduces the body's immune response, thereby preventing the rejection of transplanted organs or reducing the inflammatory response in severe eczema.
Store tacrolimus as directed on the product label, typically at room temperature away from moisture and direct sunlight. Keep it out of reach of children. Discard any unused medication after its expiration date.
Dosage is determined by your doctor based on your specific condition, weight, and response to treatment.
It is usually administered orally, but other formulations (e.g., topical) exist for specific conditions.
Never change your dose or stop taking tacrolimus without consulting your doctor.
Kidney problems (nephrotoxicity)
High blood pressure
Tremors
Headache
Nausea
Vomiting
Diarrhea
Increased risk of infections
Hyperkalemia (high potassium levels)
Diabetes
Neurological effects (e.g., seizures, confusion)
Skin reactions (e.g., rash)
Alcohol may interact with tacrolimus and increase the risk of side effects. Consult your doctor about alcohol consumption.
Tacrolimus can cause side effects like dizziness, drowsiness, and tremor, affecting your ability to drive or operate machinery. Avoid these activities if affected.
Tacrolimus can harm a developing fetus. It can also be present in breast milk. Discuss the risks and benefits with your doctor before taking tacrolimus if you are pregnant, planning pregnancy, or breastfeeding.
Dosage is adjusted based on weight and condition. Close monitoring by a doctor is required.
Tacrolimus can impair kidney function. Regular monitoring of kidney function is necessary.
Liver disease can affect tacrolimus metabolism. Dosage adjustments may be necessary.
Please consult your physician or pharmacist for detailed information and references to relevant medical literature.
