Is the main active ingredient. formulations may include inactive ingredients that vary depending on the specific brand and preparation (e.g., fillers, binders, preservatives).
Prevention of organ rejection after kidney, liver, or heart transplantation.
Treatment of severe atopic dermatitis (eczema) that has not responded to other treatments.
Tacrolimus Capsule Ip 0.25 Mg (Tacrolimus) is an immunosuppressant that works by inhibiting calcineurin, a protein involved in T-cell activation. By suppressing the immune system, it reduces the risk of organ rejection and inflammation in autoimmune diseases.
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children. Dispose of any unused medication properly according to your pharmacist's instructions.
Dosage is individualized and determined by your doctor based on your condition, weight, and response to treatment.
Tacrolimus is typically administered orally (as capsules or solution) or intravenously (in hospital settings).
Never change your dosage without consulting your doctor.
Kidney problems (increased creatinine levels)
High blood pressure
Tremor
Headache
Nausea
Diarrhea
Increased risk of infection
Diabetes
Hyperkalemia (high potassium levels)
Neurotoxicity (in high doses)
Avoid excessive alcohol consumption as it can interact with tacrolimus and increase the risk of side effects.
Tacrolimus can cause drowsiness, dizziness, or visual disturbances. Avoid driving or operating machinery if affected.
Consult your doctor before using tacrolimus if you are pregnant, breastfeeding, or planning to become pregnant. It's generally avoided during pregnancy.
Dosage adjustments are necessary in children. Use under strict medical supervision.
Tacrolimus is nephrotoxic (harmful to kidneys). Regular monitoring of kidney function is crucial.
Liver function should also be closely monitored as tacrolimus can affect liver function.
Your doctor or pharmacist
The medication package insert
Reputable medical websites (e.g., Mayo Clinic, NHS)
