Prescription Required.Why?
A sulfonylurea drug that stimulates the pancreas to release more insulin.
A biguanide drug that improves insulin sensitivity and reduces glucose production by the liver.
Type 2 diabetes mellitus, particularly when diet and exercise alone are insufficient to control blood sugar levels.
Used in patients who need a combination of medications to achieve better glycemic control.
Gliclazide increases insulin secretion from the pancreas, while metformin enhances insulin sensitivity in peripheral tissues and reduces hepatic glucose production. Their combined action leads to improved blood glucose control.
Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
Dosage should be determined by a physician based on individual needs and response.
Typically started at a low dose and gradually increased as needed.
Administered orally, usually once or twice daily with meals to minimize gastrointestinal side effects.
Lactic acidosis (rare but serious): Characterized by fatigue, muscle pain, and difficulty breathing.
Hypoglycemia (low blood sugar): Symptoms include sweating, trembling, dizziness, confusion, and weakness.
Gastrointestinal upset: Nausea, vomiting, diarrhea, and abdominal pain are common, especially with metformin.
Weight gain (possible)
Allergic reactions (rare)
Alcohol can increase the risk of hypoglycemia and lactic acidosis. Limit alcohol intake.
Hypoglycemia can impair alertness and reaction time. Avoid driving or operating machinery if experiencing hypoglycemia.
Use is generally not recommended during pregnancy or breastfeeding. Consult with a doctor immediately.
Not typically used in children.
Metformin is contraindicated or requires dose adjustment in patients with moderate to severe kidney disease.
Caution is advised in patients with liver disease; may require dose adjustments.
Consult your doctor or pharmacist for complete prescribing information and references.
Please note this information is for general knowledge and does not replace professional medical advice.
