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Prescription Required.Why?
Dimethyl fumarate is the active ingredient in medications like Tecfidera and others.Specific formulations may contain additional inactive ingredients (excipients) that vary depending on the brand and dosage form. Check the product label for a complete list.
Treatment of relapsingremitting multiple sclerosis (MS)
May be used as an alternative for patients who have not responded to or cannot tolerate other MS therapies
Sclerifuma 120 Cap (Dimethyl Fumarate) is thought to work by modulating multiple immune pathways. It reduces the activity of certain immune cells that contribute to MS pathology. The exact mechanism isn't fully understood but it involves anti-inflammatory and neuroprotective effects.
Store at room temperature, away from moisture and direct sunlight. Protect from light and heat. Keep the medication in its original container.
Dosage should be determined by your doctor and may vary based on individual needs and response to treatment.
Dimethyl fumarate is typically taken orally, usually twice daily.
It's crucial to follow your doctor's instructions precisely, including the prescribed dose, timing, and duration of treatment.
Flushing (redness and warmth in the face, neck, and chest)
Lymphopenia (low levels of lymphocytes, a type of white blood cell)
Progressive Multifocal Leukoencephalopathy (PML): A rare but potentially fatal brain infection. Your doctor will monitor you for this.
Nausea
Diarrhea
Gastrointestinal upset
Elevation of liver enzymes
Skin reactions
Moderate alcohol consumption may be permissible but should be discussed with your doctor.
Dimethyl fumarate may cause dizziness or fatigue. Avoid driving or operating machinery until you know how the medication affects you.
Not recommended during pregnancy or breastfeeding. Discuss risks and benefits with your doctor.
Not approved for use in children.
Caution is advised in patients with impaired kidney function. Dosage adjustments may be necessary.
Caution is advised in patients with impaired liver function. Close monitoring is required.
Your doctor or pharmacist
The medication's package insert (check the label)
National Multiple Sclerosis Society (NMSS)
