Prescription Required.
Is the active ingredient in medications containing this drug formulation.
Prevention of organ rejection after kidney, heart, or liver transplantation.
Treatment of certain types of cancer, such as renal cell carcinoma and neuroendocrine tumors.
Treatment of lymphangioleiomyomatosis (LAM), a rare lung disease.
Rocas 1mg Tab (Sirolimus) works by inhibiting the mTOR (mammalian target of rapamycin) pathway, which is involved in cell growth and proliferation. By blocking this pathway, sirolimus helps to prevent the body's immune system from attacking the transplanted organ.
Sirolimus medications should be stored at room temperature, away from light and moisture. Keep it out of the reach of children and pets. Do not use it after the expiration date.
Dosage and administration of sirolimus will vary depending on the specific condition being treated and the patient's individual needs.
It is typically taken by mouth, once daily, with or without food.
Your doctor will determine the appropriate dosage and frequency for you.
It's essential to take sirolimus exactly as prescribed and to not miss any doses.
Increased risk of infection
High blood pressure
High cholesterol
Kidney problems
Lung problems
Mouth sores
Diarrhea
Nausea
Vomiting
Headache
Fatigue
Rash
Wound healing problems
Alcohol consumption should be avoided or limited while taking sirolimus, as it can increase the risk of side effects.
Sirolimus may cause drowsiness, dizziness, or blurred vision. Avoid driving or operating machinery until you know how this medication affects you.
Sirolimus is not recommended during pregnancy or breastfeeding. It can harm the developing fetus or infant.
The safety and effectiveness of sirolimus in children have not been established.
Sirolimus can affect kidney function. Your doctor may monitor your kidney function while taking this medication.
Sirolimus can affect liver function. Your doctor may monitor your liver function while taking this medication.
https://www.mayoclinic.org/drugs-supplements/sirolimus-oral-route/description/drg-20070525
https://www.accessdata.fda.gov/drugsatfda_docs/label/2001/021040s000lbl.pdf
https://www.ncbi.nlm.nih.gov/pubmed/11461564
