Prescription Required.Why?
An anti-tuberculosis medication that inhibits mycobacterial cell wall synthesis.
Another anti-tuberculosis drug that interferes with mycolic acid synthesis.
A broad-spectrum antibiotic belonging to the penicillin class, effective against various gram-negative and some gram-positive bacteria.
A powerful anti-tuberculosis antibiotic that inhibits bacterial rna synthesis.
Treatment of tuberculosis (TB) infections, particularly those with suspected resistance to other TB drugs.
Treatment of severe bacterial infections, where Piperacillin's broad spectrum is needed, in conjunction with TB treatment.
This combination therapy works through multiple mechanisms. Ethambutol and Rifampicin directly target Mycobacterium tuberculosis, while Isoniazid inhibits the synthesis of mycolic acids crucial for the bacterial cell wall. Piperacillin combats a wide range of bacterial infections that might co-exist or complicate TB treatment.
Store in a cool, dry place, protected from light and moisture. Keep out of reach of children. Check expiry date before use. Dispose of unused medication appropriately.
Dosage must be determined and prescribed by a physician based on individual patient factors including age, weight, kidney and liver function, and the specific infection being treated.
Typically administered orally, though the specific route for each drug may vary.
Strict adherence to the prescribed dosage and frequency is crucial for effective treatment and to minimize adverse effects.
Ethambutol: Optic neuritis (visual disturbances), nausea, vomiting.
Isoniazid: Peripheral neuropathy (numbness, tingling), hepatitis (liver inflammation).
Piperacillin: Diarrhea, nausea, vomiting, allergic reactions (rash, itching, swelling), increased risk of Clostridium difficile infection.
Rifampicin: Orange discoloration of urine, feces, and body fluids, nausea, vomiting, liver enzyme elevation.
Avoid alcohol consumption, especially during treatment with Isoniazid, as it can increase the risk of liver damage.
May cause drowsiness or visual disturbances (especially with Ethambutol). Do not drive or operate machinery if affected.
Use only under strict medical supervision. Discuss risks and benefits with your doctor.
Dosage adjustments are necessary based on weight and age. Requires close monitoring.
Dosage adjustments may be needed for patients with impaired kidney function. Monitor renal function regularly.
Close monitoring of liver function is essential due to potential hepatotoxicity (liver damage) from Isoniazid and Rifampicin.
Please consult your doctor or pharmacist for specific references and detailed information on the individual medications.
