Isoniazid

An antibiotic used to treat tuberculosis (tb).

Pyridoxine

A vitamin that helps prevent side effects of isoniazid, specifically neuropathy (nerve damage).

Rifampicin

Another antibiotic used to treat tb. it works by inhibiting bacterial rna synthesis.

Treatment of tuberculosis (TB), specifically active pulmonary and extrapulmonary TB.

Part of a multidrug regimen to improve treatment efficacy and prevent resistance.

Isoniazid inhibits the synthesis of mycolic acids, essential components of the mycobacterial cell wall. Rifampicin inhibits bacterial DNA-dependent RNA polymerase, blocking RNA synthesis. Pyridoxine counteracts the peripheral neuropathy induced by isoniazid.

Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children. Check the expiry date before use.

Dosage is determined by a physician based on the individual's age, weight, and medical condition.

The medication is typically taken orally, usually once daily.

The exact dosage and duration of treatment will be prescribed by your doctor and should be strictly followed.

Do not stop taking the medication without consulting your physician.

Nausea

Vomiting

Loss of appetite

Dizziness

Jaundice (yellowing of skin and eyes)

Peripheral neuropathy (tingling, numbness in extremities)

Liver damage (rare but serious)

Allergic reactions (rash, itching, swelling)

Changes in urine color (redorange)

Flulike symptoms

Alcohol Consumption

Alcohol consumption should be avoided or minimized during treatment as it can increase the risk of liver damage.



While Driving or operating Machinery

May cause dizziness or drowsiness; avoid driving or operating machinery if affected.



Pregnant & Breastfeeding Women

Use only under strict medical supervision as it can cross the placental barrier and is excreted in breast milk. Risks and benefits should be carefully weighed.



Children

Dosage is adjusted based on the child's age and weight under strict medical supervision.



Kidney

Dose adjustments may be necessary for individuals with impaired kidney function.



Liver

Liver function tests should be monitored regularly, especially in individuals with pre-existing liver conditions, as the medication can cause liver damage.

Consult your physician or pharmacist for specific references and detailed prescribing information.