Clozapine

Is the active ingredient in the medication.

Treatment of schizophrenia in patients who have not responded adequately to other antipsychotic medications.

Treatment of severe, refractory schizophrenia with a high risk of aggressive behavior.

Refract 25mg Tab (Clozapine) is an atypical antipsychotic that works by blocking the effects of dopamine and serotonin in the brain. It helps to reduce hallucinations, delusions, and other symptoms of schizophrenia.

Store clozapine at room temperature, away from light and moisture. Keep it out of the reach of children and pets.

The dosage of clozapine is determined by your doctor and is based on your individual needs and response to the medication.

It is typically taken orally once or twice a day, with or without food.

Do not stop taking clozapine without talking to your doctor, even if you are feeling better.

It's crucial to follow the dosage instructions provided by your doctor and pharmacist precisely.

Serious side effects can occur, such as seizures, agranulocytosis (a serious blood disorder), myocarditis (inflammation of the heart muscle), and neuroleptic malignant syndrome (NMS).

It's important to contact your doctor immediately if you experience any severe or unusual side effects.

Common side effects include drowsiness, dizziness, constipation, dry mouth, weight gain, and increased saliva production.

Alcohol Consumption

Avoid alcohol while taking clozapine as it can worsen side effects.



Driving or operating Machinery

Avoid driving or operating machinery until you know how clozapine affects you, as it can cause drowsiness.



Pregnant & Breastfeeding Women

Clozapine can harm an unborn baby. It's not recommended for pregnant or breastfeeding women.



Children

Clozapine is not approved for use in children.



Kidney

Clozapine may need to be adjusted for patients with kidney problems.



Liver

Clozapine may need to be adjusted for patients with liver problems.

https://www.mayoclinic.org/diseases-conditions/schizophrenia/diagnosis-treatment/drc-20354222

https://www.webmd.com/schizophrenia/guide/clozapine-for-schizophrenia

https://www.ncbi.nlm.nih.gov/pubmed/12388494