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Is the active ingredient in this medication.
Prothionamide is an antituberculosis medication used to treat multidrug-resistant tuberculosis (MDR-TB) infections.
It is typically used in combination with other medications to improve effectiveness.
Protokox 250mg Tablet (Prothionamide) works by inhibiting the synthesis of mycolic acids, which are essential components of the cell wall of Mycobacterium tuberculosis. This disrupts the growth and survival of the bacteria.
Store prothionamide at room temperature, protected from light and moisture. Keep it out of reach of children.
The dosage and duration of treatment with prothionamide will vary depending on the severity of your infection, your overall health, and other factors.
Your doctor will determine the appropriate dosage for you.
Prothionamide is typically taken orally.
Follow your doctor's instructions carefully.
Common side effects of prothionamide include nausea, vomiting, diarrhea, loss of appetite, and headache.
More serious side effects can occur, such as liver damage, peripheral neuropathy, and psychosis.
Avoid alcohol consumption while taking prothionamide, as it can increase the risk of liver damage.
Prothionamide may cause dizziness, drowsiness, or other side effects that can impair your ability to drive or operate machinery. Avoid driving or operating machinery until you know how this medication affects you.
Prothionamide is not recommended for use during pregnancy. It may harm the developing fetus. It is also not recommended for use during breastfeeding, as it can pass into breast milk and may harm the nursing infant.
The safety and effectiveness of prothionamide in children have not been established.
If you have kidney problems, your doctor may need to adjust your dosage of prothionamide.
If you have liver problems, your doctor may need to monitor your liver function closely while you are taking prothionamide.
The information provided is based on publicly available sources, including the following:
https://www.drugs.com/pro/prothionamide.html
https://www.medicines.org.uk/emc/product/2883/pil
https://www.ncbi.nlm.nih.gov/pubmed/15037354
