Dosulepin

Is the primary active ingredient.

Treatment of major depressive disorder (MDD)

Treatment of anxiety disorders (e.g., generalized anxiety disorder)

Treatment of some types of chronic pain (adjunctive therapy)

Treatment of insomnia (offlabel use, requires physician's discretion)

Prothiaden 50 Tab (Dosulepin) is a tricyclic antidepressant (TCA). It works primarily by blocking the reuptake of serotonin and norepinephrine neurotransmitters in the brain, increasing their levels and improving mood and reducing anxiety symptoms.

Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children. Discard any medication that is outdated or shows signs of deterioration.

Dosage is determined by your physician and should be followed precisely.

Dosulepin is usually taken once or twice daily, typically at bedtime due to potential drowsiness.

Never abruptly stop taking Dosulepin without consulting your doctor. Dosage should be tapered gradually to minimize withdrawal symptoms.

Drowsiness

Dry mouth

Constipation

Blurred vision

Weight gain

Orthostatic hypotension (dizziness upon standing)

Sedation

Cardiac effects (rare but serious)

Allergic reactions (rash, itching, swelling)

Alcohol Consumption

Avoid alcohol consumption while taking Dosulepin as it can increase the risk of drowsiness and other side effects.



Driving or Operating Machinery

Avoid driving or operating heavy machinery until you know how Dosulepin affects you. Drowsiness is a common side effect.



Pregnant & Breastfeeding Women

Consult your doctor before taking Dosulepin if you are pregnant, breastfeeding, or planning to become pregnant. The risk-benefit ratio should be carefully considered.



Children

Dosulepin is not typically prescribed for children unless under specialist care.



Kidney

Patients with kidney impairment may require dosage adjustments. Consult your doctor.



Liver

Patients with liver impairment may require dosage adjustments. Consult your doctor.

Consult your physician or pharmacist for complete prescribing information.

Refer to reputable medical databases (e.g., PubMed) for additional scientific information.