Dinoprostone

Is a medication that belongs to the class of drugs called prostaglandins. it is a synthetic form of a naturally occurring hormone-like substance called prostaglandin e2. dinoprostone is available in various formulations, including vaginal suppositories, cervical gel, and tablets. the exact ingredients may vary depending on the specific brand and formulation.

Induction of labor: Dinoprostone is commonly used to induce labor in pregnant women who are at or near term (typically 39 weeks or later) and whose cervix is unfavorable (not ready for labor).

Cervical ripening: Dinoprostone can also be used to soften and dilate the cervix (the opening of the uterus) in preparation for labor induction or other procedures.

Termination of pregnancy: In certain circumstances, dinoprostone may be used to help terminate a pregnancy.

Management of missed miscarriage: Dinoprostone can be used to help expel the uterine contents in cases of missed miscarriage.

Primigyn 0.5mg/3.0gm Gel (Dinoprostone) works by stimulating the muscles in the uterus to contract. This helps to soften and dilate the cervix, as well as to induce labor. It also helps to reduce the risk of complications during labor, such as a cesarean section.

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Store dinoprostone at room temperature, away from heat and moisture.

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Keep dinoprostone out of reach of children and pets.

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Do not use dinoprostone if it has expired or if the packaging is damaged.

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Dispose of dinoprostone properly when it is no longer needed.

The dosage of dinoprostone will vary depending on the reason for use, the patient's individual needs, and the specific formulation being used. It is important to follow your doctor's instructions carefully. Dinoprostone is typically administered vaginally as a suppository or gel.

Common side effects: Nausea, vomiting, diarrhea, fever, chills, headache, back pain, abdominal pain, uterine contractions, vaginal bleeding, and increased vaginal discharge.

Serious side effects: Allergic reaction (rash, itching, swelling, difficulty breathing), low blood pressure, heart problems, seizures, and uterine rupture.

Alcohol Consumption

It is generally recommended to avoid alcohol consumption while taking dinoprostone, as alcohol can interact with the medication and increase the risk of side effects.



While Driving or Operating Machinery

Dinoprostone can cause dizziness, drowsiness, and other side effects that may impair your ability to drive or operate machinery. Avoid these activities until you know how dinoprostone affects you.



Pregnant & Breastfeeding Women

Dinoprostone is used for labor induction and is not typically prescribed for other conditions during pregnancy. It is not recommended for use during breastfeeding as it may pass into breast milk.



Children

Dinoprostone is not recommended for use in children.



Kidney

Dinoprostone should be used with caution in patients with kidney disease.



Liver

Dinoprostone should be used with caution in patients with liver disease.

https://www.mayoclinic.org/diseases-conditions/labor-induction/syc-20354432

https://www.ncbi.nlm.nih.gov/pubmed/26734198

https://www.drugs.com/pro/dinoprostone.html