Primaquine

Phosphate is the active ingredient in primaquine formulations. the specific inactive ingredients may vary depending on the product formulation (tablet, liquid, etc.) and manufacturer. always check the product label for a complete list of ingredients.

Treatment and prophylaxis of malaria caused by Plasmodium vivax and Plasmodium ovale (species that form hypnozoites in the liver).

Treatment of relapses of malaria caused by Plasmodium vivax and Plasmodium ovale.

Primaquine Phosphate Tablets Ip 7.5 Mg (Primaquine) targets the liver stages of Plasmodium vivax and Plasmodium ovale malaria parasites (hypnozoites), preventing relapse. It also has some activity against blood-stage parasites, but its primary action is against the dormant liver forms.

Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children. Discard any unused medication after the expiration date.

Dosage varies depending on the indication (treatment or prophylaxis), the patient's age, weight, and overall health. Dosage must be determined and monitored by a physician.

It is typically administered orally.

Never exceed the prescribed dose.

Gastrointestinal upset (nausea, vomiting, abdominal pain)

Headache

Dizziness

Shortness of breath

Methaemoglobinaemia

Cyanosis

Alcohol Consumption

Alcohol consumption may increase the risk of liver damage and should be avoided or minimized while taking Primaquine.



While Driving or operating Machinery

Primaquine may cause dizziness and drowsiness; avoid driving or operating machinery until you know how this medication affects you.



Pregnant & Breastfeeding Women

Primaquine should be avoided during pregnancy and breastfeeding unless the benefits outweigh the potential risks. Discuss use with your doctor.



Children

Dosage adjustments are necessary for children. A physician must determine the appropriate dose.



Kidney

Patients with impaired kidney function may require dose adjustment. Renal function should be monitored.



Liver

Patients with impaired liver function may require dose adjustment. Liver function should be monitored. Primaquine should be used with caution in patients with pre-existing liver disease.

Consult your physician or pharmacist for complete prescribing information and references.