Pregabalin: An anticonvulsant and analgesic medication used to treat nerve pain (neuropathic pain), fibromyalgia, and epilepsy.

Duloxetine: A serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant used to treat major depressive disorder, generalized anxiety disorder, and fibromyalgia.

Treatment of neuropathic pain (nerve pain)

Management of fibromyalgia symptoms

Treatment of generalized anxiety disorder (in combination therapy)

Pregabalin binds to calcium channels in the central nervous system, reducing the release of neurotransmitters involved in pain signaling. Duloxetine increases levels of serotonin and norepinephrine in the brain, impacting mood, pain perception, and anxiety.

Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children. Dispose of unused medication properly.

Dosage will be determined by your doctor based on your individual needs and condition.

Follow your doctor's prescription exactly and do not adjust dosage without their consultation.

It may be taken with or without food, but consistency is important.

The medicine is generally taken orally

Dizziness

Somnolence (sleepiness)

Headache

Dry mouth

Nausea

Constipation

Weight gain

Increased sweating

Fatigue

Blurred vision

Difficulty with coordination

Alcohol Consumption

Avoid alcohol consumption while taking this medication, as it can increase the risk of drowsiness and dizziness.



While Driving or Operating Machinery

Do not drive or operate machinery until you know how this medication affects you. Drowsiness is a common side effect.



Pregnant & Breastfeeding Women

Consult your doctor before taking this medication if you are pregnant, breastfeeding, or planning to become pregnant. The risk-benefit ratio needs careful consideration.



Children

This medication is not typically prescribed for children unless specifically indicated by a physician.



Kidney

Kidney function should be monitored, especially in patients with impaired renal function; dosage adjustment might be required.



Liver

Liver function should be monitored, especially in patients with impaired hepatic function; dosage adjustment might be required.

Consult your physician or pharmacist for detailed information and specific references.