Prevention of atherothrombotic events in patients with acute coronary syndrome (ACS) who are undergoing percutaneous coronary intervention (PCI)
Prevention of cardiovascular events in patients with a history of myocardial infarction, stroke, or peripheral artery disease
Prasugrel is a potent antiplatelet agent that irreversibly inhibits platelet aggregation by blocking the P2Y12 ADP receptor. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits platelet aggregation by irreversibly inhibiting cyclooxygenase-1 (COX-1). This combination provides dual antiplatelet action, reducing the risk of blood clots forming in arteries.
Store at room temperature, protected from light and moisture. Keep out of reach of children.
The usual starting dose is 10 mg prasugrel once daily, taken with or without food, along with aspirin 75-100 mg once daily.
Dosage may be adjusted based on individual patient factors and the severity of the condition.
Do not crush, break, or chew the prasugrel tablets.
Swallow the tablet whole with water.
Headache
Dizziness
Diarrhea
Nausea
Bruising
Rash
Itching
Alcohol can increase the risk of bleeding. Avoid excessive alcohol consumption.
Prasugrel may cause dizziness or drowsiness. Avoid driving or operating machinery if you experience these symptoms.
Prasugrel is not recommended for use during pregnancy or breastfeeding. Consult with your doctor before taking this medication if you are pregnant or breastfeeding.
Prasugrel is not recommended for use in children.
Caution is advised in patients with kidney disease.
Caution is advised in patients with liver disease.
Effient (prasugrel) Prescribing Information
Aspirin (acetylsalicylic acid) Prescribing Information
National Institutes of Health (NIH)
