Dihydrochloride is the active ingredient in most pramipexole formulations. specific inactive ingredients vary depending on the formulation (tablet, film-coated tablet, etc.) and manufacturer. always check the medication label for a complete list of ingredients.
Treatment of Parkinson's disease (to alleviate symptoms such as tremor, rigidity, bradykinesia, and postural instability)
Treatment of moderate to severe Restless Legs Syndrome (RLS)
Pramirol 1mg Tab (Pramipexole) is a dopamine agonist. It mimics the effects of dopamine, a neurotransmitter that plays a crucial role in movement control and the regulation of sleep-wake cycles. By binding to dopamine receptors in the brain, pramipexole helps alleviate the symptoms of Parkinson's disease and RLS.
Store pramipexole tablets in a tightly closed container at room temperature (below 25°C/77°F), away from moisture, light, and extreme temperatures. Keep out of reach of children. Discard any unused medication according to the instructions provided by your pharmacist or healthcare provider.
Dosage is determined by your doctor and is individualized based on your condition and response to treatment.
Start with a low dose and gradually increase as directed by your physician.
Pramipexole is typically taken orally, usually once or twice daily with or without food.
Nausea
Vomiting
Dizziness
Sleepiness (somnolence)
Hallucinations
Constipation
Insomnia
Fatigue
Drowsiness
Confusion
Sudden sleep attacks (in rare cases)
Alcohol may increase the risk of drowsiness and other side effects. Avoid alcohol consumption while taking pramipexole.
Pramipexole may cause drowsiness, dizziness, and impaired judgment. Avoid driving or operating machinery until you know how pramipexole affects you.
Use during pregnancy is not recommended unless the potential benefits outweigh the risks. Consult your doctor. Pramipexole may pass into breast milk and may affect the nursing infant.
Pramipexole is not generally recommended for use in children.
Patients with kidney impairment may require dose adjustments. Kidney function should be monitored.
Pramipexole is primarily metabolized by the kidneys, so significant liver impairment usually does not require dose adjustments. However, always inform your doctor of any liver problems.
Your doctor or pharmacist
The medication package insert
Reputable medical websites (e.g., Mayo Clinic, NHS)
