Capsaicin

A naturally occurring chemical found in chili peppers, known for its analgesic and counter-irritant effects. it works by depleting substance p, a neurotransmitter involved in pain signaling.

Menthol

A naturally occurring compound derived from mint oils. it acts as a counter-irritant, creating a cooling sensation that can temporarily mask pain.

Methyl Salicylate

A synthetic derivative of salicylic acid (aspirin's active ingredient). it functions as a counter-irritant and has mild analgesic properties.

Piroxicam

A nonsteroidal anti-inflammatory drug (nsaid) that reduces inflammation and pain by inhibiting cyclooxygenase (cox) enzymes.

Relief of localized muscle and joint pain associated with conditions such as arthritis, sprains, strains, and backache.

Temporary relief of minor aches and pains.

This combination drug formulation works through a multi-pronged approach. Capsaicin depletes substance P, reducing pain signals. Menthol and methyl salicylate act as counter-irritants, creating a distraction from pain through a cooling or warming sensation. Piroxicam, an NSAID, reduces inflammation and pain by inhibiting COX enzymes.

Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.

Apply a thin layer to the affected area.

Rub gently into the skin.

Repeat as needed, but do not exceed the recommended number of applications per day (as specified on the product label).

Wash hands thoroughly after application.

Skin irritation (burning, redness, itching)

Allergic reactions (rash, hives, swelling)

Increased sensitivity to sunlight

Gastrointestinal upset (if ingested)

Alcohol Consumption

Avoid excessive alcohol consumption while using this medication as it may increase the risk of gastrointestinal side effects, particularly with Piroxicam.



While Driving or Operating Machinery

Use caution while driving or operating machinery, especially if experiencing dizziness or drowsiness (though this is less common with topical application).



Pregnant & Breastfeeding Women

Consult your doctor before using this medication if you are pregnant or breastfeeding.



Children

Consult a pediatrician before use in children.



Kidney

Use with caution in individuals with kidney problems due to Piroxicam's potential impact on kidney function. Consult your doctor.



Liver

Use with caution in individuals with liver problems due to the potential for liver effects with Piroxicam. Consult your doctor.

Product label information

Physician's Desk Reference (PDR)

Relevant medical journals and databases (List specific citations if possible - adapt this section depending on the specific formulation and available references)