Sevelamer

Sevelamer is the active ingredient in medications like Renvela, Renagel, and others.It belongs to a class of drugs called phosphate binders.Sevelamer works by binding to phosphate in the gut, preventing it from being absorbed into the bloodstream.

Hyperphosphatemia (high phosphate levels in the blood) in patients with chronic kidney disease (CKD) on dialysis.

To help control phosphate levels in patients with CKD not on dialysis.

May be used to help reduce the risk of cardiovascular disease in CKD patients.

Phosphout 400 Tablet (Sevelamer) is a non-absorbable polymer that binds to phosphate in the digestive tract. This binding prevents the phosphate from being absorbed into the bloodstream, thus lowering phosphate levels in the blood.

Store sevelamer tablets at room temperature, away from moisture and heat. Keep them in their original container.

The dosage of sevelamer is determined by your doctor and may vary depending on your condition and individual needs.

It is usually taken by mouth with meals.

It is important to take sevelamer exactly as prescribed by your doctor.

Do not crush or chew the tablets.

Swallow the tablets whole with a full glass of water.

Hypocalcemia (low calcium levels in the blood)

Constipation

Diarrhea

Nausea

Vomiting

Abdominal pain

Gas

Decreased vitamin D absorption

Allergic reactions

Alcohol Consumption

It is generally safe to consume alcohol while taking sevelamer, but it's advisable to consult with your doctor.



While Driving or operating Machinery

Sevelamer does not usually affect alertness or coordination, but you should consult with your doctor if you experience any side effects that may impair your ability to drive.



Pregnant & Breastfeeding Women

The safety of sevelamer during pregnancy and breastfeeding has not been fully established. Consult with your doctor before using sevelamer if you are pregnant, breastfeeding, or planning to become pregnant.



Children

Sevelamer is generally safe for children when used under the guidance of a doctor.



Kidney

Sevelamer is used to treat hyperphosphatemia in patients with kidney disease, but it's crucial to use it under the guidance of a doctor.



Liver

Sevelamer is generally safe for patients with liver disease, but your doctor may adjust the dosage based on your condition.

https://www.mayoclinic.org/drugs-supplements/sevelamer-oral-route/description/drg-20067786

https://www.fda.gov/drugs/drug-safety-and-availability/fda-approves-generic-version-sevelamer-hydrochloride-oral-suspension-treat-high-phosphate-levels-patients

https://www.ncbi.nlm.nih.gov/pubmed/15249507