Fluorouracil

Is the primary active ingredient. specific formulations may contain additional excipients like preservatives, stabilizers, and solvents depending on the route of administration (e.g., topical cream, intravenous solution, tablets).

Treatment of various cancers, including colorectal cancer, breast cancer, stomach cancer, and others. Specific indications vary based on the formulation and stage of the cancer.

Used alone or in combination with other chemotherapy drugs.

May be used topically for certain skin conditions.

Oncofluor 500mg/10ml Inj (Fluorouracil) is an antimetabolite that inhibits the synthesis of DNA and RNA, ultimately preventing cancer cell growth and proliferation. It works by interfering with the action of thymidylate synthase, an enzyme crucial for DNA replication.

Store according to the specific instructions on the product label. Generally, this involves keeping the medication at a controlled room temperature, away from direct sunlight and moisture. Dispose of unused medication properly as per healthcare provider's instructions.

Dosage is highly individualized and determined by the healthcare provider based on factors like tumor type, stage of disease, overall health, and response to treatment.

Routes of administration include intravenous infusion, topical application, and oral tablets (less common).

Never alter the dosage or frequency without consulting a doctor.

Nausea and vomiting

Diarrhea

Mouth sores (stomatitis)

Fatigue

Hair loss (alopecia)

Handfoot syndrome (palmar-plantar erythrodysesthesia)

Myelosuppression (decreased blood cell counts)

Increased risk of infection

Neurotoxicity (peripheral neuropathy)

Alcohol Consumption

Alcohol consumption may exacerbate side effects, particularly gastrointestinal distress. Consult your doctor.



While Driving or operating Machinery

Fluorouracil can cause fatigue and neurological side effects that impair coordination and judgment. Avoid driving or operating machinery if affected.



Pregnant & Breastfeeding Women

Fluorouracil is highly teratogenic (can cause birth defects). It's contraindicated in pregnancy and breastfeeding women. Effective contraception is necessary.



Children

Use in children is determined on a case-by-case basis, typically only in specific cancer treatments and under strict medical supervision.



Kidney

Renal impairment may necessitate dosage adjustments or alternative treatments. Close monitoring of kidney function is crucial.



Liver

Hepatic impairment may affect drug metabolism and increase the risk of toxicity. Liver function monitoring is recommended.

Physician's Desk Reference (PDR)

National Cancer Institute (NCI)

Relevant medical journals and clinical trials (specify if available)