Fluoxetine

A selective serotonin reuptake inhibitor (ssri) antidepressant.

Olanzapine

An atypical antipsychotic medication.

Treatment of major depressive disorder (MDD) with significant symptoms of anxiety.

Management of acute manic or mixed episodes associated with bipolar I disorder.

Fluoxetine increases serotonin levels in the brain by inhibiting its reuptake, while olanzapine blocks dopamine and serotonin receptors, reducing psychotic symptoms and mood instability. The combination is thought to provide broader symptomatic relief than either drug alone in certain conditions.

Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children. Discard any medication that is outdated or shows signs of deterioration.

Dosage should be determined by a healthcare professional and tailored to individual needs.

It's crucial to follow the prescribed dosage and frequency exactly as directed by your doctor or pharmacist.

Do not abruptly stop taking the medication; gradually reduce the dose under medical supervision.

Orthostatic hypotension (low blood pressure upon standing)

Weight gain

Drowsiness or sedation

Dry mouth

Constipation

Blurred vision

Increased appetite

Nausea

Dizziness

Sexual dysfunction

Increased risk of metabolic syndrome

Alcohol Consumption

Avoid alcohol consumption, as it can potentiate the sedative effects of both medications and increase the risk of side effects.



Driving or Operating Machinery

Avoid driving or operating machinery until you know how this medication affects you. Drowsiness is a common side effect.



Pregnant & Breastfeeding Women

Inform your doctor immediately if you are pregnant, breastfeeding, or planning to become pregnant. The risks and benefits of using this medication during pregnancy and breastfeeding must be carefully weighed.



Children

Not typically prescribed for children unless explicitly indicated by a specialist and under strict monitoring.



Kidney

Requires caution in patients with kidney impairment; dosage adjustments may be necessary.



Liver

Requires caution in patients with liver impairment; dosage adjustments may be necessary.

Package insert provided by the manufacturer.

Physician's Desk Reference (PDR)

Relevant clinical guidelines from organizations like the FDA and NICE (referencing specific guidelines would strengthen this)