A broad-spectrum antibiotic effective against a wide range of bacteria.
An antibiotic effective against gram-negative bacteria, particularly pseudomonas aeruginosa.
Treatment of serious bacterial infections, particularly those caused by Gramnegative bacteria resistant to other antibiotics.
Topical treatment of certain eye infections (depending on formulation).
Chloramphenicol inhibits bacterial protein synthesis, while Polymyxin B disrupts bacterial cell membranes, leading to bacterial cell death. Their combined action provides broader antimicrobial coverage.
Store at controlled room temperature (20-25°C). Protect from light and moisture. Discard any unused medication after the expiry date.
Dosage is determined by the physician based on the severity of the infection, patient's age, weight, and renal function.
Administration routes vary depending on the specific formulation (e.g., intravenous, topical).
Strictly follow the prescribed dosage and schedule; do not exceed the recommended dose.
Gray baby syndrome (in newborns)
Gastrointestinal disturbances (nausea, vomiting, diarrhea)
Neurotoxicity (confusion, seizures)
Nephrotoxicity (kidney damage)
Hypersensitivity reactions (allergic reactions)
Avoid alcohol consumption as it may exacerbate side effects.
May cause drowsiness or dizziness; avoid driving or operating machinery if affected.
Use only if clearly needed and under strict medical supervision. Chloramphenicol can cross the placenta and is excreted in breast milk.
Use with extreme caution, especially in newborns due to the risk of gray baby syndrome.
Reduce dosage in patients with kidney impairment.
Monitor liver function regularly during treatment.
Consult your physician or pharmacist for detailed information and specific references related to the specific formulation of Chloramphenicol + Polymyxin B you are using.
Refer to the package insert for your specific medicine.
