Hydrochloride is the active ingredient in clomipramine medications. the specific formulation (e.g., tablet, capsule) may contain inactive ingredients like fillers, binders, and coatings which vary depending on the manufacturer.
Major depressive disorder (MDD)
Obsessivecompulsive disorder (OCD)
Panic disorder
Other anxiety disorders (in some cases, as determined by a healthcare professional)
Ocifril 50mg Tab (Clomipramine) is a tricyclic antidepressant (TCA). It primarily works by increasing the levels of serotonin and norepinephrine in the brain. These neurotransmitters play crucial roles in mood regulation, anxiety levels, and impulse control. The precise mechanisms contributing to its efficacy in OCD are not fully understood, but likely involve modulation of serotonin pathways in brain regions associated with compulsive behaviors.
Store clomipramine at room temperature, away from moisture and direct sunlight. Keep it out of reach of children and pets. Dispose of expired or unwanted medication properly, following your pharmacist's or local regulations.
Dosage is determined by your doctor based on your condition and response to treatment.
It's typically started at a low dose and gradually increased as needed.
Clomipramine is usually taken once or twice daily, with or without food, as directed by your physician.
Do not stop taking clomipramine suddenly without consulting your doctor. Gradual tapering is usually necessary to minimize withdrawal symptoms.
Dry mouth
Constipation
Drowsiness or sedation
Blurred vision
Orthostatic hypotension (dizziness upon standing)
Weight gain
Sexual dysfunction
Increased sweating
Tremors
Alcohol should be avoided or limited while taking clomipramine, as it can enhance sedative effects and increase the risk of side effects.
Clomipramine may cause drowsiness or dizziness. Avoid driving or operating machinery until you know how it affects you.
Clomipramine should be used during pregnancy or breastfeeding only if the potential benefits outweigh the potential risks. Discuss this with your doctor.
Clomipramine is not typically used in children, except in specific situations and under close medical supervision.
Clomipramine may require dosage adjustment in patients with impaired kidney function.
Clomipramine may require dosage adjustment in patients with impaired liver function.
Your physician or pharmacist
Reputable medical websites (e.g., Mayo Clinic, NHS, MedlinePlus)
The official prescribing information (package insert) provided with your medication.
