Tobramycin

Is an aminoglycoside antibiotic.

Treatment of serious infections caused by susceptible strains of aerobic gramnegative bacteria.

Often used in combination with other antibiotics for synergistic effect.

Treatment of certain types of pneumonia, urinary tract infections, intraabdominal infections, and septicemia.

Obrin Eye Oint 5gm (Tobramycin) inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, leading to misreading of mRNA and ultimately preventing bacterial growth and replication.

Store at controlled room temperature (20-25°C/68-77°F). Protect from light and moisture. Discard any unused portion after the expiry date.

Dosage is determined by the severity of the infection, patient's renal function, and the specific formulation (e.g., intravenous, intramuscular, or topical).

Always follow the prescription instructions provided by your doctor or healthcare professional.

Intravenous administration requires careful monitoring of blood levels to avoid toxicity.

Do not discontinue the medication prematurely, even if you feel better. Completing the full course of treatment is crucial to prevent recurrence of infection.

Nephrotoxicity (kidney damage)

Ototoxicity (hearing loss or balance problems)

Nausea

Vomiting

Diarrhea

Rash

Hypersensitivity reactions (allergic reactions)

Alcohol Consumption

Avoid alcohol consumption as it can increase the risk of side effects, especially liver damage if Tobramycin is given in combination with other hepatotoxic drugs.



While Driving or operating Machinery

May cause dizziness or drowsiness; avoid driving or operating machinery if affected.



Pregnant & Breastfeeding Women

Use only when the benefits outweigh the potential risks to the fetus or infant. Consult your doctor.



Children

Dosage adjustments may be necessary based on age and weight.



Kidney

Requires careful dose adjustment or alternative medication in patients with impaired renal function. Regular monitoring of kidney function is crucial.



Liver

Monitor liver function, particularly if combined with other hepatotoxic medications.

Please consult your physician or pharmacist for complete prescribing information and updated drug interactions.