Amitriptyline

A tricyclic antidepressant (tca) that works by increasing the levels of certain natural chemicals in the brain.

Pregabalin

An anticonvulsant and analgesic medication that works by reducing the release of certain chemicals in the brain that cause pain signals.

Treatment of neuropathic pain, such as diabetic neuropathy and postherpetic neuralgia

Management of generalized anxiety disorder (GAD)

Treatment of major depressive disorder (MDD), especially when other antidepressants have been ineffective

Neugatrip Tab (Amitriptyline + Pregabalin) work together to provide relief from pain and anxiety symptoms. Amitriptyline increases the levels of serotonin and norepinephrine in the brain, which are neurotransmitters involved in mood regulation and pain perception. Pregabalin inhibits the release of glutamate and GABA, neurotransmitters that play a role in pain signaling and anxiety.

Store this medication in a cool, dry place, away from direct sunlight and heat. Keep it out of reach of children and pets. Dispose of unused medication responsibly.

The dosage of amitriptyline and pregabalin will vary depending on the individual patient and their condition.

Your doctor will determine the appropriate dosage for you.

It is important to take this medication exactly as prescribed by your doctor.

Do not increase or decrease the dosage without consulting your doctor.

Increased risk of seizures in individuals with epilepsy

Drowsiness

Dizziness

Dry mouth

Constipation

Blurred vision

Weight gain

Sexual dysfunction

Increased appetite

Sleepiness

Confusion

Headache

Weakness

Fatigue

Nausea

Vomiting

Heart palpitations

Alcohol Consumption

Avoid alcohol consumption while taking this medication, as it can increase the risk of side effects, including drowsiness and dizziness.



While Driving or operating Machinery

Avoid driving or operating machinery until you know how this medication affects you. It can cause drowsiness and impaired alertness.



Pregnant & Breastfeeding Women

This medication should be used with caution during pregnancy and breastfeeding. Consult with your doctor before taking this medication if you are pregnant or breastfeeding.



Children

This medication is not typically prescribed for children. Consult with your doctor before giving this medication to children.



Kidney

This medication can be affected by kidney function. Your doctor may need to adjust the dosage if you have kidney problems.



Liver

This medication can be affected by liver function. Your doctor may need to adjust the dosage if you have liver problems.

https://www.mayoclinic.org/diseases-conditions/neuropathic-pain/symptoms-causes/syc-20352416

https://www.ncbi.nlm.nih.gov/pubmed/20640924

https://www.webmd.com/drugs/2/drug-15228/amitriptyline-oral/details

https://www.webmd.com/drugs/2/drug-15135/pregabalin-oral/details