Prescription Required.Why?
An antiemetic (prevents nausea and vomiting) and prokinetic (increases gut motility) agent.
An analgesic (pain reliever) and antipyretic (fever reducer).
An opioid analgesic (pain reliever) with both opioid and non-opioid mechanisms of action.
Moderate to severe pain where other analgesics are insufficient.
Nausea and vomiting associated with pain.
Pain accompanied by fever.
Domperidone blocks dopamine receptors in the chemoreceptor trigger zone and gut, reducing nausea and vomiting and improving gastric emptying. Paracetamol reduces fever by acting on the hypothalamus and reduces pain through unclear mechanisms, possibly involving inhibition of cyclooxygenase (COX) enzymes. Tramadol inhibits the reuptake of norepinephrine and serotonin, and also acts as a weak opioid agonist, providing analgesia.
Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children. Discard any expired medication.
Always follow the prescription provided by your doctor.
Do not exceed the recommended dosage.
Take the medication with or without food, as advised by your doctor.
Rarely: allergic reactions, seizures, respiratory depression (especially with higher doses of Tramadol).
Domperidone related: prolonged QT interval (heart rhythm abnormality, requires ECG monitoring in some cases). This risk is generally low at therapeutic doses.
Nausea, vomiting, constipation, drowsiness, dizziness, headache, dry mouth.
Avoid alcohol consumption as it can increase the risk of drowsiness and other side effects, particularly with Tramadol.
Avoid driving or operating machinery until you know how this medication affects you. Drowsiness and dizziness are possible side effects.
Consult your doctor before taking this medication if you are pregnant, breastfeeding, or planning to become pregnant. Tramadol, in particular, is not typically recommended during pregnancy or breastfeeding unless the benefits clearly outweigh the risks.
Dosage should be adjusted based on the child's age and weight. Consult a pediatrician before giving this medication to a child.
Renal impairment may require dose adjustment. Consult your physician.
Hepatic impairment may require dose adjustment. Consult your physician.
Please consult your doctor or pharmacist for detailed information and specific references. This information is for general knowledge and should not be considered medical advice.
