Trimethoprim is an antibiotic that belongs to a class of drugs called folate reductase inhibitors.It works by interfering with the production of a vital substance called folic acid, which bacteria need to grow and multiply.Trimethoprim is often combined with sulfamethoxazole, another antibiotic, to create a medication called co-trimoxazole (also known as Bactrim or Septra).Co-trimoxazole is commonly prescribed for various bacterial infections.
Urinary tract infections (UTIs)
Pneumocystis jirovecii pneumonia (PCP) in people with weakened immune systems, such as those with HIV/AIDS
Other bacterial infections, such as bronchitis, otitis media (ear infections), and traveler's diarrhea, depending on the specific strain of bacteria involved.
Nacsitol 100mg Tablet (Trimethoprim) inhibits the enzyme dihydrofolate reductase (DHFR), which is essential for the synthesis of tetrahydrofolic acid. Tetrahydrofolic acid is a coenzyme required for the synthesis of DNA and other essential compounds in bacteria. By inhibiting DHFR, trimethoprim disrupts the bacterial growth and multiplication process.
Store trimethoprim at room temperature, away from moisture and heat.
Keep the medication in its original container.
Do not use trimethoprim after the expiration date printed on the label.
Keep trimethoprim out of reach of children and pets.
The dosage of trimethoprim will vary depending on the specific infection being treated, the patient's age, weight, and overall health.
It is crucial to follow your doctor's instructions carefully and take the medication exactly as prescribed.
Trimethoprim is typically taken by mouth, usually with a glass of water.
Do not crush, chew, or open the capsules or tablets unless instructed by your doctor.
Increased risk of seizures in patients with certain medical conditions
Nausea
Vomiting
Diarrhea
Headache
Dizziness
Rash
Itching
Allergic reactions, such as hives, swelling, difficulty breathing (anaphylaxis)
Blood disorders, such as anemia, neutropenia, thrombocytopenia
Liver damage
Kidney damage
Consuming alcohol while taking trimethoprim may increase the risk of side effects, including liver damage.
Trimethoprim can cause dizziness and drowsiness, which may impair your ability to drive or operate machinery safely.
Trimethoprim should only be used during pregnancy if the potential benefits outweigh the risks to the unborn child. It can pass into breast milk and may harm the nursing infant. Consult your doctor before taking trimethoprim if you are pregnant or breastfeeding.
Trimethoprim is generally safe for children, but the dosage should be adjusted based on their age and weight.
Trimethoprim can be harmful to the kidneys, especially in people with pre-existing kidney problems. Your doctor may need to monitor your kidney function while taking trimethoprim.
Trimethoprim can also be harmful to the liver. Your doctor may need to monitor your liver function while taking trimethoprim.
https://www.medicines.org.uk/emc/medicine/2680/SPC/trimethoprim
https://www.mayoclinic.org/drugs-supplements/trimethoprim-oral-route/description/drg-20067446
https://www.drugs.com/trimethoprim.html
