Prescription Required.Why?
Is the primary active ingredient.
Rheumatoid arthritis
Psoriatic arthritis
Juvenile idiopathic arthritis
Certain types of cancer (e.g., choriocarcinoma, lymphoma)
Severe psoriasis
Crohn's disease
Ectopic pregnancy
Methotrexate Tablets Ip 10mg (Methotrexate) is an antifolate drug. It inhibits dihydrofolate reductase, an enzyme crucial for DNA synthesis and cell division. By interfering with this process, it slows the growth of rapidly dividing cells, including cancer cells and immune cells involved in inflammatory diseases.
Store methotrexate at room temperature, away from moisture and direct sunlight. Keep it out of reach of children. Discard any unused medication as instructed by your pharmacist or healthcare provider.
Dosage is highly individualized and determined by your doctor based on your condition, weight, and response to treatment.
Methotrexate can be administered orally, intravenously, or intramuscularly.
Never adjust your dosage without consulting your doctor.
Nausea
Vomiting
Diarrhea
Mouth sores
Fatigue
Headache
Hair loss
Liver damage (rare but serious)
Kidney damage (rare but serious)
Pneumonitis (inflammation of the lungs)
Increased risk of infection
Alcohol consumption should be minimized or avoided entirely while taking methotrexate, as it can increase the risk of liver damage.
Methotrexate can cause fatigue and drowsiness. Avoid driving or operating machinery if affected.
Methotrexate is teratogenic (causes birth defects). It is contraindicated during pregnancy and breastfeeding. Reliable contraception is essential.
Methotrexate is used in children with certain conditions, but dosage is carefully adjusted by a specialist.
Methotrexate can impair kidney function; regular monitoring of kidney function is crucial, especially with high doses.
Methotrexate can cause liver damage; regular liver function tests are necessary.
Your doctor and pharmacist
The prescribing information (package insert) provided with your medication.
Reputable medical websites such as the National Institutes of Health (NIH) and Mayo Clinic.
