Metasub 60mg Tab: Price, Use, Benefit, Side Effect

Metasub 60mg Tab

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Zee Laboratories

Composition

Trimetazidine (60mg)

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About Metasub 60mg Tab

Metasub 60mg Tab (Trimetazidine) is a medication used to treat chronic stable angina. It works by altering the heart's energy metabolism to reduce oxygen demand and improve energy supply. Common side effects include nausea, vomiting, and dizziness. It's crucial to follow your doctor's prescribed dosage and to inform them of any pre-existing medical conditions, especially kidney or liver problems. Avoid driving or operating machinery if you experience dizziness. Always consult your physician before using this medication during pregnancy, breastfeeding, or if you have any concerns.

Ingredients

Directions for Use

How Drug Works

Storage & Handling

Drug Dosage

Side Effects

Safety Consideration or Warnings

References

Ingredients of Metasub 60mg Tab

Trimetazidine

Dihydrochloride

Direction for Use of Metasub 60mg Tab

Treatment of chronic stable angina pectoris (chest pain) in patients who are inadequately controlled by, or intolerant of, other antianginal treatments.

Prevention of angina attacks.

How Metasub 60mg Tab Works

Metasub 60mg Tab (Trimetazidine) inhibits the long-chain 3-ketoacyl-CoA thiolase enzyme, an enzyme involved in fatty acid oxidation. By inhibiting this enzyme, it shifts myocardial energy metabolism from fatty acid oxidation to glucose oxidation, thus improving myocardial energy supply and reducing oxygen demand. This helps to reduce the frequency and severity of angina attacks.

Storage and Handling of Metasub 60mg Tab

Store at room temperature (20-25°C). Protect from moisture and light. Keep out of the reach of children.

Dosage of Metasub 60mg Tab

Dosage should be determined by a physician.

The usual starting dose is 35 mg twice daily (morning and evening).

The dose may be increased to 70 mg twice daily if needed, but only as per doctor’s instruction.

Side effects of Metasub 60mg Tab

Nausea

Vomiting

Abdominal pain

Headache

Dizziness

Fatigue

Insomnia

Safety Consideration or Warnings

Alcohol Consumption

The interaction between trimetazidine and alcohol is not well documented, but it's advisable to limit alcohol consumption as excessive alcohol can have negative effects on heart health.

While Driving or operating Machinery

Trimetazidine can cause dizziness and fatigue. Avoid driving or operating machinery if you experience these side effects.

Pregnant & Breastfeeding Women

The use of trimetazidine during pregnancy and breastfeeding should only be considered if the potential benefits outweigh the potential risks. Consult with a doctor before using this medication during pregnancy or breastfeeding.

Children

The safety and effectiveness of trimetazidine in children have not been established.

Kidney

Renal impairment may affect the elimination of trimetazidine, requiring dose adjustment. Consult with a doctor if you have kidney problems.

Liver

There is limited information on how the liver affects the metabolism and excretion of trimetazidine. Consult with a doctor if you have liver problems.

References

Consult your physician or pharmacist for detailed information and references.

Please refer to the patient information leaflet provided with your medication.

Last Updated On 21 Dec. 2025 | 11:41 PM (IST)

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