Mesalazine, also known as 5-aminosalicylic acid (5-ASA), is the active ingredient in these medications.It may be combined with other ingredients like delayed-release or extended-release formulations to target specific areas of the digestive tract.
Ulcerative colitis (UC): To control symptoms and prevent flare-ups.
Crohn's disease: To treat inflammation in the colon and ileum.
Proctitis: Inflammation of the rectum.
Mesacol 1g Suppositories (Mesalazine) works by reducing inflammation in the digestive tract. It is thought to act by blocking the production of certain chemicals that contribute to inflammation.
Store mesalazine medications at room temperature, away from moisture and direct sunlight.
Dosage varies depending on the specific medication, your condition, and your doctor's instructions.
It is typically taken orally, with or without food.
Follow your doctor's instructions carefully and do not change your dosage without consulting them.
Less common side effects: fever, rash, and joint pain.
Serious side effects: severe allergic reactions, liver problems, and low blood cell counts. Seek immediate medical attention if you experience any of these.
Common side effects: headache, nausea, stomach pain, diarrhea, and constipation.
Moderate alcohol consumption is generally safe, but excessive alcohol use may worsen digestive symptoms. Consult your doctor for personalized advice.
Mesalazine generally does not impair alertness or coordination. However, if you experience side effects such as dizziness, drowsiness, or vision changes, avoid driving or operating machinery.
Mesalazine should only be used during pregnancy if the potential benefit outweighs the risk to the fetus. Consult your doctor for advice. Mesalazine can pass into breast milk, but it is generally safe for breastfeeding mothers.
The safety and effectiveness of mesalazine in children have not been established. Use under strict medical supervision.
Mesalazine may affect kidney function, especially if you have pre-existing kidney disease. Your doctor may monitor your kidney function regularly.
Mesalazine may cause liver problems in rare cases. If you experience any symptoms of liver problems, such as yellowing of the skin or eyes, contact your doctor immediately.
https://www.mayoclinic.org/diseases-conditions/ulcerative-colitis/diagnosis-treatment/drc-20353523
https://www.webmd.com/digestive-disorders/crohns-disease/features/crohns-disease-medications
https://www.fda.gov/drugs/information-on-drugs/mesalamine-oral-route
