Midazolam

Is the main active ingredient. specific formulations may include other inactive ingredients such as preservatives, stabilizers, and solvents which vary depending on the drug product (e.g., oral solution, injection). always check the product label for a complete list of ingredients.

Sedation before medical procedures (e.g., endoscopy, surgery)

Treatment of seizures (status epilepticus)

Premedication for anesthesia

Sedation in intensive care units (ICU)

Treatment of insomnia (in some cases, under strict medical supervision)

Medistat Nasal Spray (Midazolam) is a benzodiazepine that enhances the effects of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain. This increases GABAergic inhibition, resulting in sedation, anxiolysis, muscle relaxation, and anticonvulsant effects.

Store at room temperature, away from direct sunlight and moisture. Keep out of reach of children. Discard any unused medication according to your pharmacist's or doctor's instructions. Do not use if the medication is expired or shows signs of degradation.

Dosage is highly individualized and determined by a physician based on factors such as age, weight, medical condition, and the specific indication. It is crucial to strictly follow the prescribed dosage and administration instructions.

Midazolam can be administered intravenously, intramuscularly, rectally, orally, or via nasal spray. The route of administration will depend on the medical need and the patient's condition.

Drowsiness

Dizziness

Confusion

Weakness

Headache

Nausea

Vomiting

Respiratory depression (rare but serious)

Amnesia (memory loss)

Alcohol Consumption

Avoid alcohol consumption while taking midazolam as it can significantly increase the risk of sedation and respiratory depression.



While Driving or operating Machinery

Do not drive or operate machinery until you know how midazolam affects you. It can impair judgment, coordination, and reaction time.



Pregnant & Breastfeeding Women

Use during pregnancy only if the potential benefit outweighs the risk to the fetus. It can pass into breast milk and may affect the nursing infant.



Children

Dosage adjustments are needed for children. Use only as directed by a pediatrician.



Kidney

Dosage adjustments may be needed for patients with kidney impairment.



Liver

Dosage adjustments are usually needed for patients with liver impairment, as the liver is the primary site of metabolism for midazolam.

Please consult your physician or pharmacist for specific references and updated information on midazolam.