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Matibenz 400 Tablet
Matibenz 400 Tablet
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Marketer
Admac Pharma Ltd
Composition
Imatinib Mesylate (400mg)
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About Matibenz 400 Tablet
Matibenz 400 Tablet (Imatinib Mesylate) is a medication used to treat certain types of cancer, including chronic myeloid leukemia (CML), Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), gastrointestinal stromal tumors (GISTs), and some types of advanced systemic mastocytosis. It works by blocking the activity of a specific protein that helps cancer cells grow. It is typically taken orally, once daily, and the dosage is determined by your doctor based on your individual needs. Common side effects include nausea, vomiting, diarrhea, muscle aches, fatigue, and swelling. It is important to follow your doctor's instructions regarding the use of this medication, including dosage and potential interactions with other medications. If you experience any side effects, it is important to contact your doctor immediately.
Ingredients of Matibenz 400 Tablet

    Imatinib Mesylate

    Imatinib mesylate is the active ingredient in the medication.It belongs to a class of drugs called tyrosine kinase inhibitors.

Direction for Use of Matibenz 400 Tablet

    Chronic myeloid leukemia (CML) in chronic phase, accelerated phase, or blast crisis.

    Philadelphia chromosomepositive acute lymphoblastic leukemia (Ph+ ALL) in adults and children.

    Gastrointestinal stromal tumors (GISTs) that are unresectable or metastatic.

    Certain types of advanced systemic mastocytosis.

How Matibenz 400 Tablet Works

Matibenz 400 Tablet (Imatinib Mesylate) works by blocking the activity of a specific protein called BCR-ABL tyrosine kinase. This protein is abnormally active in CML and Ph+ ALL, and it helps cancer cells grow and spread. By blocking this protein, imatinib mesylate helps to slow down or stop the growth of cancer cells.

Storage and Handling of Matibenz 400 Tablet

Store imatinib mesylate at room temperature, between 20°C and 25°C (68°F and 77°F). Keep it in its original container, tightly closed, and away from light and moisture.

Dosage of Matibenz 400 Tablet

    The dosage of imatinib mesylate will be determined by your doctor based on your individual needs and medical condition.

    It is typically taken orally, once daily with or without food.

    It is important to take imatinib mesylate exactly as prescribed by your doctor and to complete the full course of treatment, even if you feel better.

Side effects of Matibenz 400 Tablet

    Nausea

    Vomiting

    Diarrhea

    Muscle aches

    Fatigue

    Swelling in the legs or ankles

    Skin rash

    Headache

    Fluid retention

Safety Consideration or Warnings
    Alcohol Consumption

    It is generally recommended to avoid alcohol while taking imatinib mesylate as it can potentially increase the risk of side effects.

    While Driving or Operating Machinery

    Imatinib mesylate may cause fatigue or dizziness, which can affect your ability to drive or operate machinery. Do not drive or operate machinery if you experience these symptoms.

    Pregnant & Breastfeeding Women

    Imatinib mesylate can harm an unborn baby. It is not recommended for pregnant women. It is also not recommended for breastfeeding mothers as it can pass into breast milk.

    Children

    Imatinib mesylate is used in children with certain types of leukemia, but it is not safe for all children. Your doctor will carefully consider the risks and benefits of treatment for your child.

    Kidney

    Imatinib mesylate is primarily eliminated from the body through the kidneys. If you have kidney problems, your doctor may need to adjust your dose.

    Liver

    Imatinib mesylate can also affect the liver. Your doctor may monitor your liver function during treatment.

References

    https://www.fda.gov/drugs/resources-information-approved-drugs/gleevec-imatinib-mesylate

    https://www.cancer.gov/publications/dictionaries/cancer-terms/def/imatinib

    https://www.mayoclinic.org/diseases-conditions/chronic-myeloid-leukemia/diagnosis-treatment/drc-20353811

Frequently Asked Questions (FAQs)
How long do I need to take Matibenz 400 Tablet (Imatinib Mesylate)?
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Last Updated On 08 May. 2025 | 05:15 PM (IST)
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₹2,235.00
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₹2,235.00
(₹223.5 per unit)
For 10 Paint (s)
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