Prescription Required.Why?
Rifampicin (the active ingredient)Other inactive ingredients may vary depending on the specific formulation (check product label)
Treatment of tuberculosis (TB)
Treatment of leprosy (Hansen's disease)
Prophylaxis (prevention) of meningococcal disease
Treatment of other bacterial infections (as prescribed by a doctor)
Macox 450mg Cap (Rifampicin) is a broad-spectrum antibiotic that inhibits bacterial DNA-dependent RNA polymerase. This prevents bacterial RNA synthesis, ultimately leading to bacterial cell death.
Store at room temperature, protected from light and moisture. Keep out of reach of children. Discard any unused medication after the expiry date.
Dosage varies greatly depending on the specific infection, patient age, weight, and kidney/liver function. Always follow your doctor's prescription.
Rifampicin is typically administered orally (by mouth).
Do not stop taking the medication without consulting your doctor, even if you feel better.
Complete the full course of treatment as prescribed.
Orange discoloration of urine, sweat, and tears (harmless)
Nausea
Vomiting
Abdominal pain
Loss of appetite
Fatigue
Headache
Dizziness
Rash
Itching
Liver damage (rare but serious)
Flulike symptoms
Alcohol may interact with rifampicin and increase the risk of liver damage. Consult your doctor about alcohol consumption while taking this medication.
Rifampicin may cause dizziness or drowsiness. Avoid driving or operating machinery if affected.
Rifampicin can cross the placenta and be present in breast milk. Discuss the risks and benefits with your doctor before using during pregnancy or breastfeeding.
Dosage adjustments are necessary for children. Always follow your doctor's prescription.
Kidney impairment may require dosage adjustment. Your doctor will monitor your kidney function.
Rifampicin can affect liver function. Regular liver function tests may be needed during treatment.
Your doctor or pharmacist
The medication's package insert
Reputable medical websites (e.g., Mayo Clinic, NHS)
