Magnesium valproate is the magnesium salt of valproic acid.It contains valproate as the active pharmaceutical ingredient (API).Formulations may include inactive ingredients such as cellulose, lactose, magnesium stearate, etc. Always check the specific product labeling.
Treatment of epilepsy and seizure disorders (various types)
Treatment of bipolar disorder (manicdepressive illness)
Migraine prophylaxis (prevention of migraine headaches)
The exact mechanism isn't fully understood, but Macorate Cr 400mg Tab (Magnesium Valproate) is believed to increase levels of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain. This helps reduce neuronal excitability and prevent seizures.
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Dosage is determined by a physician based on the patient's age, weight, condition, and response to treatment.
It is typically administered orally, with or without food.
The prescribed dosage should be followed precisely; never adjust the dosage without consulting a doctor.
Nausea and vomiting
Weight gain
Hair loss
Tremor
Drowsiness
Liver problems (rare but serious)
Pancreatitis (rare but serious)
Blood disorders (rare but serious)
Alcohol should be avoided or severely limited while taking magnesium valproate as it can increase the risk of side effects.
Avoid driving or operating machinery until you know how this medication affects you. Drowsiness is a possible side effect.
Magnesium valproate can cause serious birth defects. It is generally avoided during pregnancy and breastfeeding unless the benefits outweigh the risks. Discuss with your doctor immediately if you are pregnant or plan to become pregnant.
Dosage is adjusted based on weight and condition and is carefully monitored by a physician.
Renal impairment may necessitate dosage adjustments. Your doctor should monitor your kidney function.
Liver function tests are often performed periodically, especially during the initial stages of treatment, as liver damage is a rare but serious potential side effect.
Consult your physician or pharmacist for further information and current prescribing information.
Reputable medical websites (e.g., NIH, FDA).
