Gemcitabine

Gemcitabine is the active ingredient in this medication.It is a type of chemotherapy drug known as an antimetabolite.Gemcitabine works by interfering with the growth of cancer cells.

Gemcitabine is used to treat a variety of cancers, including:

Pancreatic cancer

Nonsmall cell lung cancer

Breast cancer

Ovarian cancer

Bladder cancer

Other solid tumors.

Jupibine 200 Injection (Gemcitabine) is a nucleoside analog that interferes with the synthesis of DNA, which is essential for cell growth and replication. Specifically, it inhibits the enzyme ribonucleotide reductase, which is responsible for converting ribonucleotides to deoxyribonucleotides. This process blocks the synthesis of DNA and ultimately leads to cell death. By targeting rapidly dividing cancer cells, gemcitabine effectively inhibits tumor growth.

Store gemcitabine at room temperature, between 15°C and 30°C (59°F and 86°F). Protect it from light and moisture. Keep it out of reach of children and pets. Do not flush unused medications down the toilet or pour them into a drain unless instructed to do so by your healthcare provider.

The dosage of gemcitabine will vary depending on your specific condition, your overall health, and other factors.

It is typically given intravenously (into a vein) over a period of 30 minutes.

Nausea and vomiting

Diarrhea

Low white blood cell count (neutropenia)

Low red blood cell count (anemia)

Low platelet count (thrombocytopenia)

Fatigue

Hair loss

Mouth sores

Skin rash

Lung problems (pneumonitis)

Kidney problems

Liver problems

Heart problems

Alcohol Consumption

Avoid alcohol consumption while taking gemcitabine, as it can increase the risk of liver damage.



While Driving or Operating Machinery

Gemcitabine can cause fatigue and other side effects that may impair your ability to drive or operate machinery. Do not drive or operate machinery until you know how this medication affects you.



Pregnant & Breastfeeding Women

Gemcitabine is known to harm an unborn baby. Do not take gemcitabine if you are pregnant or breastfeeding. Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.



Children

Gemcitabine is not typically used in children. Consult with your doctor for specific instructions.



Kidney

Gemcitabine can affect your kidney function. Your doctor will monitor your kidney function closely.



Liver

Gemcitabine can affect your liver function. Your doctor will monitor your liver function closely.

National Cancer Institute: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/gemcitabine

Drugs.com: https://www.drugs.com/mtm/gemcitabine.html

Mayo Clinic: https://www.mayoclinic.org/diseases-conditions/pancreatic-cancer/diagnosis-treatment/drc-20355291