Is the active ingredient.
Treatment of negative and positive symptoms of schizophrenia.
Treatment of acute manic episodes in bipolar disorder.
Joypride 400mg Tab (Amisulpride) is a dopamine D2 and D3 receptor antagonist. It selectively blocks dopamine D2 receptors in the mesolimbic pathway (associated with positive symptoms) and has a lower affinity for D2 receptors in the nigrostriatal pathway (reducing the risk of extrapyramidal side effects). Its action on D3 receptors may contribute to its efficacy in treating negative symptoms.
Store below 25°C. Protect from moisture and light. Keep out of reach of children.
Dosage and frequency should be determined by a healthcare professional based on individual patient needs and response.
Typically, oral administration.
Dosage adjustments may be necessary for patients with kidney or liver impairment.
Extrapyramidal symptoms (e.g., parkinsonism, akathisia, dystonia)
Hyperprolactinemia (increased prolactin levels, leading to galactorrhea, amenorrhea, gynecomastia)
Sedation or drowsiness
Weight gain
Orthostatic hypotension
Neuroleptic malignant syndrome (rare but serious)
Nausea, vomiting, constipation
Alcohol should be avoided or consumed in moderation as it can increase the risk of sedation and other side effects.
Patients should avoid driving or operating machinery until they know how Amisulpride affects their ability to perform these activities. Sedation and dizziness are possible side effects.
Use during pregnancy and breastfeeding is generally not recommended unless the potential benefits outweigh the risks. Discuss with your doctor.
Use in children is not typically recommended.
Dosage adjustment may be necessary in patients with kidney impairment.
Dosage adjustment may be necessary in patients with liver impairment.
Please consult your physician or pharmacist for specific prescribing information and references to the relevant drug literature.
