Sildenafil is the main active ingredient.Various formulations may include additional inactive ingredients like fillers, binders, and coatings which may vary depending on the brand and dosage form (tablet, chewable, etc.). Always check the specific product labeling for a complete list of ingredients.
Treatment of pulmonary arterial hypertension (PAH) in adult men and women. (Note: Dosage and formulations for PAH treatment differ significantly from those for ED.)
Treatment of erectile dysfunction (ED) in adult men.
Josh On Tab (Sildenafil) inhibits phosphodiesterase type 5 (PDE5), an enzyme that breaks down cyclic GMP. Increased cyclic GMP levels relax the smooth muscles in the blood vessels of the penis, leading to improved blood flow and facilitating an erection in men with ED. In PAH, it improves blood flow to the lungs, reducing blood pressure.
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Dosage for ED is typically 50 mg as needed, approximately one hour before sexual activity. The dose may be increased to 100 mg or decreased to 25 mg based on individual response and tolerance. Do not exceed 100mg per day.
Dosage for PAH varies significantly and is determined by a physician based on individual needs and response. It is typically taken daily, not as-needed.
Always follow your doctor's instructions precisely and consult them if you have questions or concerns regarding dosage adjustments.
Visual disturbances (blurred vision, changes in color vision)
Priapism (prolonged erection; seek immediate medical attention)
Rare but serious side effects include: heart attack, stroke, irregular heartbeat, sudden hearing loss, severe skin reactions.
Headache
Flushing
Facial flushing
Nasal congestion
Dizziness
Dyspepsia (indigestion)
Muscle aches
Back pain
Alcohol can reduce blood pressure and may increase the risk of side effects, especially hypotension. Moderate alcohol consumption is generally advised. Consult with your doctor for specific recommendations.
Sildenafil may cause dizziness, blurred vision, or drowsiness. Avoid driving or operating machinery if affected.
Sildenafil is not indicated for use in pregnant or breastfeeding women.
Sildenafil is not approved for use in children.
Patients with severe kidney disease may require dose adjustment.
Patients with severe liver disease should use caution, as the drug is extensively metabolized by the liver. Dose adjustment may be needed
Your physician or pharmacist
The drug's package insert (official product information)
Reputable medical websites like the FDA or equivalent national drug agencies
Published scientific literature on Sildenafil.
